Factor de riesgo declarados e incidencia de sarcoma de Kaposi en pacientes con virus de inmunodeficiencia humana que acuden al Hospital José Daniel Rodríguez Maridueña entre el período 2012 - 2014
Fecha
2015
Autores
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Universidad de Guayaquil. Facultad de Ciencias Médicas. Escuela de Medicina
Resumen
El sarcoma de Kaposi fue descrito por primera vez en la literatura Medica por el Dermatólogo Húngaro Moritz Kaposi en 1872, quien lo denomino “ SARCOMA PIGMENTADO MULTIPLE IDIOPATICO”, Kaposi describió cinco casos de varones homosexuales portadores de VIH, describió lesiones que se caracterizaban por su proliferación vascular y fusocelular, describiendo tumores cutáneos y extracutaneos.3
También llamado angiosarcoma de Kaposi o sarcoma hemorrágico idiopático múltiple. Es una angiomatosis de evolución maligna, tumores vasculares cuya proliferación de células endoteliales estimuladas por diversas citosinas, como la Oncostatin M y diversos factores de crecimiento.
El sarcoma asociado a SIDA se caracteriza por tener una distribución simétrica y multicentrica y localizarse en áreas como boca, nariz, tórax y extremidades. Su aparición esta asociado con el grado de inmunodepresión del paciente, consecuencia de la infección por VIH, pudiendo ser el SK la primera manifestación de SIDA en un pequeño número de casosEn cuanto al tratamiento , en la mayoría de los casos basta con el inicio del TARGA, con lo cual se evita el progreso, disminuye las lesiones existentes.1
OBJETIVO GENERAL:
Factores de riesgo declarados e incidencia de Sarcoma de Kaposi en pacientes con virus de inmunodeficiencia humana que acuden al hospital Jose Daniel Rodriguez Maridueña entre el periodo 2012 -2014.
TIPO DE ESTUDIO:
Observacional, descriptivo, retrospectivo y transversal
ÁREA DE ESTUDIO:
Hospital de Infectologia “Jose Rodriguez Maridueña”
SUMMARY Kaposi's sarcoma was first described in the medical literature by the Dermatologist Hungarian Moritz Kaposi in 1872, whom I call "SARCOMA PIGMENTED MULTIPLE idiopathic" Kaposi described five cases of gay men with HIV, described lesions were characterized by vascular and spindle cell proliferation, describing skin and extracutaneous tumors. Also called Kaposi angiosarcoma or multiple idiopathic hemorrhagic sarcoma. It is a angiomatosis of malignant progression, vascular tumors, the proliferation of endothelial cells stimulated by various cytokines, such as Oncostatin M and various growth factors. AIDS-related sarcoma is characterized by a symmetrical distribution and multicentric and located in areas such as mouth, nose, chest and limbs. Its appearance is associated with the degree of immunosuppression of the patient, following HIV infection, SK may be the first manifestation of AIDS in a small number of casosEn terms of treatment, in most cases simply the start of HAART , which prevents progress decreases existing lesions. GENERAL PURPOSE: Reported risk factors and incidence of Kaposi's sarcoma in patients with human immunodeficiency virus who come to the hospital Jose Daniel Rodriguez Maridueña between the period 2012 -2014. TYPE OF STUDY: Observational, descriptive, retrospective and cross. STUDY AREA: Infectious Diseases Hospital "Jose Rodriguez Maridueña"
SUMMARY Kaposi's sarcoma was first described in the medical literature by the Dermatologist Hungarian Moritz Kaposi in 1872, whom I call "SARCOMA PIGMENTED MULTIPLE idiopathic" Kaposi described five cases of gay men with HIV, described lesions were characterized by vascular and spindle cell proliferation, describing skin and extracutaneous tumors. Also called Kaposi angiosarcoma or multiple idiopathic hemorrhagic sarcoma. It is a angiomatosis of malignant progression, vascular tumors, the proliferation of endothelial cells stimulated by various cytokines, such as Oncostatin M and various growth factors. AIDS-related sarcoma is characterized by a symmetrical distribution and multicentric and located in areas such as mouth, nose, chest and limbs. Its appearance is associated with the degree of immunosuppression of the patient, following HIV infection, SK may be the first manifestation of AIDS in a small number of casosEn terms of treatment, in most cases simply the start of HAART , which prevents progress decreases existing lesions. GENERAL PURPOSE: Reported risk factors and incidence of Kaposi's sarcoma in patients with human immunodeficiency virus who come to the hospital Jose Daniel Rodriguez Maridueña between the period 2012 -2014. TYPE OF STUDY: Observational, descriptive, retrospective and cross. STUDY AREA: Infectious Diseases Hospital "Jose Rodriguez Maridueña"
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Sarcoma de Kaposi, Virus de inmunodeficiencia humana, Factores de riesgo, Hospital de Infetología Dr. José Daniel Rodríguez Maridueña, Cantón Guayaquil, Ecuador