Actividad antimicótica de extractos acuosos y etanólicos de la planta senna pistaciifolia contra la presencia de candida albicans(hongos)
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2018
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Universidad de Guayaquil. Facultad de Ciencias Químicas
Resumen
Se determinó la actividad antimicótica del extracto acuoso de la planta Senna pistaciifolia contra la presencia de Candida albicans, haciendo estudios para saber si la planta es antimicótica y si es favorable para las personas que tienen este tipo de hongo. Se evaluó la presencia o ausencia de metabolitos secundarios de una especie natural; ya sea alcaloide, antraquinona y naftaquinonas, esteroides, triterpenos, flavonoides, taninos, saponinas, cumarinas y glúcosidos. El análisis se elaboró en la Facultad de Ciencias Químicas de la Universidad de Guayaquil. En este proyecto se evaluó la actividad antimicótica de extracto tanto acuoso como alcohólico de la planta Senna pistaciifolia, que fue obtenido por el métodos maceración y filtrado al vacio, el extracto acuoso con agua destilada, el extracto alcohólico con una concentración de alcohol al 70%, evaluándose la actividad antimicótica contra Candida albicans (Hongos), mediante los métodos de Kirby Bauer (discos) se determinó la difusión en agar. Se realizó el tamizaje fitoquímico evaluando la intensidad mediante el uso de cruces y de color. Encontramos que el metabolito secundario más abundante son los flavonoides (coloración rojo intenso), es moderado en glucósidos y en muy poca cantidad los taninos con ausencia de aceites esenciales, triterpenos, antraquinonas y esteroide, encontrado en el extracto alcohólico; y en el extracto acuoso se obtuvo la presencia abundante de cumarinas y moderada en alcaloides y saponinas.
The antifungal activity of the aqueous extract of the plant Senna pistaciifolia against the presence of Candida albicans was determined, making studies to know if the plant is antifungal and if it is favorable for people who have this type of fungus. The presence or absence of secondary metabolites of a natural species was evaluated; alkaloid, anthraquinone and naphthaquinones, steroids, triterpenes, flavonoids, tannins, saponins, coumarins and glycosides. The analysis was elaborated in the Faculty of Chemical Sciences of the University of Guayaquil. This project evaluated the antifungal activity of both aqueous and alcoholic extract of the Senna pistaciifolia plant, which was obtained by the maceration and vacuum filtration methods, the aqueous extract with distilled water, the alcoholic extract with an alcohol concentration at 70 %, evaluating the antifungal activity against Candida albicans (Fungi), using the Kirby Bauer methods (disks) the diffusion was determined in agar. Phytochemical screening was carried out evaluating the intensity through the use of crosses and color. We find that the most abundant secondary metabolite are flavonoids (intense red coloration), it is moderate in glycosides and in very little quantity the tannins with absence of essential oils, triterpenes, anthraquinones and steroid, found in the alcoholic extract; and in the aqueous extract the abundant presence of coumarins was obtained and moderate in alkaloids and saponins.
The antifungal activity of the aqueous extract of the plant Senna pistaciifolia against the presence of Candida albicans was determined, making studies to know if the plant is antifungal and if it is favorable for people who have this type of fungus. The presence or absence of secondary metabolites of a natural species was evaluated; alkaloid, anthraquinone and naphthaquinones, steroids, triterpenes, flavonoids, tannins, saponins, coumarins and glycosides. The analysis was elaborated in the Faculty of Chemical Sciences of the University of Guayaquil. This project evaluated the antifungal activity of both aqueous and alcoholic extract of the Senna pistaciifolia plant, which was obtained by the maceration and vacuum filtration methods, the aqueous extract with distilled water, the alcoholic extract with an alcohol concentration at 70 %, evaluating the antifungal activity against Candida albicans (Fungi), using the Kirby Bauer methods (disks) the diffusion was determined in agar. Phytochemical screening was carried out evaluating the intensity through the use of crosses and color. We find that the most abundant secondary metabolite are flavonoids (intense red coloration), it is moderate in glycosides and in very little quantity the tannins with absence of essential oils, triterpenes, anthraquinones and steroid, found in the alcoholic extract; and in the aqueous extract the abundant presence of coumarins was obtained and moderate in alkaloids and saponins.
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ANTIMICÓTICO, CANDIDA ALBICANS, EXTRACTO, MICROORGANISMOS