Evaluación de hormonas tiroideas T3, T4 Y TSH en mujeres de 18 a 30 años que usan anticonceptivos hormonales, 2017
Fecha
2018
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Universidad de Guayaquil. Facultad de Ciencias Químicas
Resumen
El presente trabajo toma como referencia un artículo publicado en la revista Medicina Interna de México en el año 2015, donde informaba acerca de las alteraciones en las pruebas de función tiroidea en usuarias de anticonceptivos hormonales, el cual es relacionado con su principio activo a base de estrógenos. Mediante una encuesta previa y parámetros de criterios de exclusión, aplicados en una población de 73 mujeres, se seleccionó a 50 mujeres de entre
18 a 30 años, que eran usuarias del Laboratorio “Alpha” del cantón La Libertad y se realizó un análisis inmunológico de niveles hormonales (T3, T4 y TSH) mediante el Test de ELISA. Con los datos obtenidos se llevó a cabo un análisis estadístico con el software IBM SPSS STATISTICS, encontrándose que las mujeres de 19 a 24 años, es decir, el 46% eran las que más usaban anticonceptivos hormonales; el 46% de ellas usaba como anticonceptivo la forma farmacéutica inyectable; el 44% llevaba menos de un año y 1 mes utilizándolo. El análisis de perfil tiroideo para T3 estableció que no se presenta ningún caso alterado, pero sí un 16% cerca del valor referencial máximo establecido por el laboratorio. Mientras que para el análisis de T4, el 20% de ellas presentaron alteraciones por encima de los valores referenciales y para el análisis de TSH no se encontró alteración. Comprobando que sí hay alteraciones con más frecuencia en la hormona T4, lo cual se ve afectado por el anticonceptivo oral.
The present work takes as reference an article published in the journal Internal Medicine of Mexico in 2015, where it reported on the alterations in thyroid function tests in users of hormonal contraceptives, which is related to its active principle based on estrogen By means of a previous survey and parameters of exclusion criteria, applied in a population of 73 women, 50 women aged between 18 and 30 years were selected, who were users of the "Alpha" Laboratory of the canton La Libertad and an immunological analysis was carried out. Hormone levels (T3, T4 and TSH) by the ELISA Test. With the data obtained, a statistical analysis was carried out with the IBM SPSS STATISTICS software, and it was found that women aged 19 to 24, that is, 46%, used hormonal contraceptives the most. 46% of them used the injectable pharmaceutical form as a contraceptive; 44% had been using it for less than a year and 1 month. The thyroid profile analysis for T3 established that no altered case is presented, but 16% close to the maximum reference value established by the laboratory. While for the analysis of T4, 20% of them presented alterations above the referential values and for the TSH analysis no alteration was found. Proving that there are alterations more frequently in the T4 hormone, which is affected by the oral contraceptive
The present work takes as reference an article published in the journal Internal Medicine of Mexico in 2015, where it reported on the alterations in thyroid function tests in users of hormonal contraceptives, which is related to its active principle based on estrogen By means of a previous survey and parameters of exclusion criteria, applied in a population of 73 women, 50 women aged between 18 and 30 years were selected, who were users of the "Alpha" Laboratory of the canton La Libertad and an immunological analysis was carried out. Hormone levels (T3, T4 and TSH) by the ELISA Test. With the data obtained, a statistical analysis was carried out with the IBM SPSS STATISTICS software, and it was found that women aged 19 to 24, that is, 46%, used hormonal contraceptives the most. 46% of them used the injectable pharmaceutical form as a contraceptive; 44% had been using it for less than a year and 1 month. The thyroid profile analysis for T3 established that no altered case is presented, but 16% close to the maximum reference value established by the laboratory. While for the analysis of T4, 20% of them presented alterations above the referential values and for the TSH analysis no alteration was found. Proving that there are alterations more frequently in the T4 hormone, which is affected by the oral contraceptive
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ANTICONCEPTIVOS HORMONALES, ESTRÓGENOS, HORMONAS TIROIDEAS, PERFIL TIROIDEO