Correlación diagnóstica entre las características ecográficas de los nódulos tiroideos y los resultado citológicos por paaf Instituto Oncológico SOLCA Dr. Juan Tanca Marengo 2013
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2014
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Universidad de Guayaquil. Facultad de Ciencias Médicas. Escuela de Graduados
Resumen
El cáncer de tiroides es la neoplasia endocrina más frecuente siendo el carcinoma papilar de tiroides el subtipo que representa el 75 – 80% de los casos. Clásicamente se lo ha considerado a este cáncer como de buen pronóstico. En los últimos años, se ha dado el aumento exponencial en su diagnóstico. El objetivo determinar en los nódulos tiroideos si existe asociación entre las variables clínica, características ecográficas y los resultados citológicos tomados a través de PAAF para definir la incidencia de neoplasia tiroidea en los pacientes del ION, SOLCA, 2013. La investigación fue de tipo descriptiva, diseño no experimental; retrospectivo. Los resultados más sobresalientes fueron: la mayoría de personas con esta patología fueron mujeres, con una baja incidencia en varones, la mayoría proviene de la región costa, tienen un bajo porcentaje de factores de riesgo: antecedentes familiares 6%, uso de hormona tiroidea 22%. La probalidad de clasificar a través de la ecografía las lesiones como maligna es menor si no se estandariza la lectura a través de clasificaciones internacionales y establecimiento de un algoritmo diagnóstico de la patología nodular tiroides. .La sensibilidad de la toma de ecografía y resultado de citología positivo es del 100%, con una especificidad del 85%, la probalidad pre test es del 6%, el VPP 30% y el VPN 100%, lo que hace recomendable la prueba para pacientes con sospecha clínica de patología tiroidea maligno, especialmente para quienes presentan factores de riesgo con edades extremas, historia familiar de cáncer, nódulo tiroideo de crecimiento rápido, disfonía, problemas respiratorios, entre otros.
Thyroid cancer is the most common endocrine neoplasia being papillary thyroid carcinoma subtype accounting for 75-80% of cases. Classically it has considered this cancer and good prognosis. In recent years, there has been an exponential increase in diagnosis. The aim thyroid nodules determine the association between the clinical variables, sonographic features and cytology results taken by FNA to define the incidence of thyroid neoplasia in patients ION, SOLCA, 2013. The research was descriptive, non-experimental design; retrospective. The most outstanding results were: Most people with this disease were women, with a low incidence in males, most comes from the coastal region, have a low percentage of risk factors: family history 6%, use of thyroid hormone 22 %. Probability with sorting through ultrasound and malignant lesions is less if reading is not standardized across international rankings and establishing a diagnosis algorithm nodular thyroid disease. .The Specificity of ultrasonography and making positive cytology result is 100%, with a specificity of 85%, the pre-test Probability is 6%, PPV 30% and NPV 100%, making recommendable to test for patients with clinically suspected malignant thyroid disease, especially those with risk factors extremes of age, family history of cancer, thyroid nodule situated, dysphonia, and respiratory problems, among others.
Thyroid cancer is the most common endocrine neoplasia being papillary thyroid carcinoma subtype accounting for 75-80% of cases. Classically it has considered this cancer and good prognosis. In recent years, there has been an exponential increase in diagnosis. The aim thyroid nodules determine the association between the clinical variables, sonographic features and cytology results taken by FNA to define the incidence of thyroid neoplasia in patients ION, SOLCA, 2013. The research was descriptive, non-experimental design; retrospective. The most outstanding results were: Most people with this disease were women, with a low incidence in males, most comes from the coastal region, have a low percentage of risk factors: family history 6%, use of thyroid hormone 22 %. Probability with sorting through ultrasound and malignant lesions is less if reading is not standardized across international rankings and establishing a diagnosis algorithm nodular thyroid disease. .The Specificity of ultrasonography and making positive cytology result is 100%, with a specificity of 85%, the pre-test Probability is 6%, PPV 30% and NPV 100%, making recommendable to test for patients with clinically suspected malignant thyroid disease, especially those with risk factors extremes of age, family history of cancer, thyroid nodule situated, dysphonia, and respiratory problems, among others.
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Nodulo tiroideo, Ultrasonografía, Biología celular, Hospital SOLCA de Guayaquil, Cantón Guayaquil, Ecuador, Neoplasias