Incidencia del dengue por medio de la técnica antígeno no estructurado (NS1) en pacientes febriles de 16 a 79 años
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2013
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Universidad de Guayaquil. Facultad de Ciencias Médicas. Carrera de Tecnología Médica
Resumen
El Dengue es una enfermedad viral aguda, transmitida por el mosquito Aedes aegypti que se cría en el agua acumulada en recipientes y objetos en desuso. Por lo que en esta tesis se expone el siguiente objetivo: Determinación de Dengue por técnica Antígeno de Dengue NS1 en pacientes febriles con el objetivo de optimizar el diagnóstico temprano del virus, para su tratamiento eficaz. En esta investigación se obtuvieron las siguientes conclusiones: El dengue es un problema creciente de salud pública a nivel mundial, la incidencia en ciertas partes de la ciudad se debe a las condiciones de vida inadecuadas y el desconocimiento en cuanto a la prevención y tratamiento de este virus. Las pruebas serológicas para los anticuerpos específicos al dengue tipos IgG e IgM, pueden ser útiles para confirmar el diagnósticos primario o secundario. Luego de un estudio de 8 meses (Enero- Agosto), de 150 pacientes estudiados un 67% que dieron positivos para NS1, fueron confirmados con IgM y se comprobó su positividad.Mujeres 48% y hombres 52%, con una frecuencia de 15 a 25 años un 39.3%, 26 a 36 años un 21.3 %, 37 a 47 años 16.6%, 48 a 58 años un 8.6%, de 59 a 69 años un 13.3% y de 70 a 80 años un 1%Dando como resultado una efectividad en las prueba, en varios niveles de edad, por lo que se recomienda el uso de esta nueva prueba para la determinación temprana de una infección del virus del Dengue.
Dengue is an acute viral disease, transmitted by the Aedes aegypti mosquito that breeds in water accumulated in containers and obsolete objects. Therefore, the following objective is set forth in this thesis: Determination of Dengue by Dengue NS1 Antigen technique in febrile patients with the objective of optimizing the early diagnosis of the virus, for its effective treatment. In this investigation the following conclusions were obtained: Dengue is a growing problem of public health worldwide, the incidence in certain parts of the city is due to inadequate living conditions and ignorance regarding the prevention and treatment of this virus. Serological tests for dengue specific IgG and IgM antibodies may be useful to confirm the primary or secondary diagnosis. After an 8-month study (January-August), of 150 patients studied, 67% who tested positive for NS1, were confirmed with IgM and their positivity was verified. Women 48% and men 52%, with a frequency of 15 to 25 years 39.3%, 26 to 36 years 21.3%, 37 to 47 years 16.6%, 48 to 58 years 8.6%, 59 to 69 years 13.3% and 70 to 80 years 1%, resulting in a test effectiveness, at various age levels, so it is recommended to use this new test for the early determination of a Dengue virus infection.
Dengue is an acute viral disease, transmitted by the Aedes aegypti mosquito that breeds in water accumulated in containers and obsolete objects. Therefore, the following objective is set forth in this thesis: Determination of Dengue by Dengue NS1 Antigen technique in febrile patients with the objective of optimizing the early diagnosis of the virus, for its effective treatment. In this investigation the following conclusions were obtained: Dengue is a growing problem of public health worldwide, the incidence in certain parts of the city is due to inadequate living conditions and ignorance regarding the prevention and treatment of this virus. Serological tests for dengue specific IgG and IgM antibodies may be useful to confirm the primary or secondary diagnosis. After an 8-month study (January-August), of 150 patients studied, 67% who tested positive for NS1, were confirmed with IgM and their positivity was verified. Women 48% and men 52%, with a frequency of 15 to 25 years 39.3%, 26 to 36 years 21.3%, 37 to 47 years 16.6%, 48 to 58 years 8.6%, 59 to 69 years 13.3% and 70 to 80 years 1%, resulting in a test effectiveness, at various age levels, so it is recommended to use this new test for the early determination of a Dengue virus infection.
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Dengue, Fiebre, Aedes aegypti, Anciano, Hospital Alcivar, Cantón Guayaquil, Ecuador, Técnica antígeno no estructurado, Adolescente, Adulto