Principales agentes etiológicos aislados en muestras de pacientes con queratomicosis, Centro Médico Sur Guayaquil, Fundación Damas del Honorable Cuerpo Consular, abril 2010 abril 2012
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2014
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Universidad de Guayaquil. Facultad de Ciencias Médicas. Escuela de Graduados
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Durante el periodo comprendido entre abril del 2010 y abril del 2012 se realizó la investigación en el Laboratorio de Microbiología del Centro Médico Sur “Fundación Damas del Honorable Cuerpo Consular”, con el objetivo de la identificación de los principales agentes etiológicos aislados en muestras de pacientes con queratomicosis, mediante la utilización de procedimientos microbiológicos de cultivo e identificación. La población en estudio fue conformada por 105 pacientes que cumplieron con los criterios de inclusión, donde se encontraron 66 casos (62.86%) positivos para queratomicosis. Los principales agentes etiológicos detectados fueron: Fusarium con el 53,03%, Aspergillus con el 28,79%, Cándida con el 15,15% y otros géneros (Curvularia y Alternaría) el 3,03%. La mayor afectación por los agentes micóticos se encontró en pacientes del sexo masculino con el 57,14%. Según el grupo de edad, el que aportó mayor número de casos, fue el grupo de 41-50 años (46.67%), seguido por los pacientes mayores de 51 años (33.33%). De los pacientes atendidos, según su ocupación, correspondió a los agricultores y jornaleros el 30,48%; a los albañiles y ebanistas el 24,76%; amas de casa y comerciantes el 19,05%; estudiantes y oficinistas el 13,33% y al grupo de otras ocupaciones el 12,38%.
En relación a la susceptibilidad a los antifúngicos probados, del total de los 10 cepas de C. albicans recuperadas, todas fueron sensibles a los antifúngicos AMB, FCY, ECN, CKA, CLO, MIC, ITR, VOR, FLU de 64 µIm; para la NY 8 fueron sensibles y 2 resistentes; para el FLU de 16 µIm 5 cepas se mostraron sensibles y 5 resistentes.
During the period between April 2010 and April 2012 the research was conducted in the Laboratory of Microbiology Medical Center South" Honorable Ladies of the Consular Corps Foundation" , with the aim of identifying the main etiological agents isolated in samples from patients with keratomycosis , using microbiological cultivation and identification methods . The study population was comprised of 105 patients who met the inclusion criteria, where 66 cases (62.86 %) were found positive for fungal keratitis. The main etiologic agents were detected: 53.03% with Fusarium, Aspergillus with 28.79%, 15.15% with Cándida and other genres (Curvularia and Alternaria) 3.03%. The most affected by fungal agents was found in male patients with 57.14 %. Depending on the age group, which brought more cases, was the group of 41-50 years (46.67%), followed by patients older than 51 years (33.33%). Of the patients treated, by occupation, farmers accounted for 30.48 % and laborers, masons and carpenters to the 24.76%, housewives and businessmen 19.05%, 13.33 students and office workers % and the group of other occupations 12.38 %. In relation to susceptibility to antifungal agents tested , the total of the 10 strains of C. albicans recovered, all were susceptible to antifungal agents AMB , FCY , NEC, CKA , CLO , MIC, ITR , VOR, FLU 64 μIm , NY for 8 were sensitive and 2 resistant ; FLU for 16 μIm 5 strains were sensitive and 5 resilient.
During the period between April 2010 and April 2012 the research was conducted in the Laboratory of Microbiology Medical Center South" Honorable Ladies of the Consular Corps Foundation" , with the aim of identifying the main etiological agents isolated in samples from patients with keratomycosis , using microbiological cultivation and identification methods . The study population was comprised of 105 patients who met the inclusion criteria, where 66 cases (62.86 %) were found positive for fungal keratitis. The main etiologic agents were detected: 53.03% with Fusarium, Aspergillus with 28.79%, 15.15% with Cándida and other genres (Curvularia and Alternaria) 3.03%. The most affected by fungal agents was found in male patients with 57.14 %. Depending on the age group, which brought more cases, was the group of 41-50 years (46.67%), followed by patients older than 51 years (33.33%). Of the patients treated, by occupation, farmers accounted for 30.48 % and laborers, masons and carpenters to the 24.76%, housewives and businessmen 19.05%, 13.33 students and office workers % and the group of other occupations 12.38 %. In relation to susceptibility to antifungal agents tested , the total of the 10 strains of C. albicans recovered, all were susceptible to antifungal agents AMB , FCY , NEC, CKA , CLO , MIC, ITR , VOR, FLU 64 μIm , NY for 8 were sensitive and 2 resistant ; FLU for 16 μIm 5 strains were sensitive and 5 resilient.
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Queratomicosis, Aspergilosis, Noxas, Fundación Damas del Honorable Cuerpo Consular. Centro Médico Sur, Cantón Guayaquil, Ecuador