Lesiones histológicas frecuentes vistas en biopsia renal de pacientes con nefropatía diabética, Hospital General Luis Vernaza en el año 2014
Fecha
2015
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Universidad de Guayaquil. Facultad de Ciencias Médicas. Carrera de Medicina
Resumen
Introducción: La Diabetes y su complicación crónica más frecuente como es la Nefropatía Diabética resultan ser un problema grave de salud pública ya q esta última es causa común de enfermedad renal crónica terminal lo que conlleva a sugerir tratamiento especializado como diálisis, sea esta peritoneal o hemodiálisis, lo que da como consecuencia que la tasa de morbilidad, mortalidad y gastos económicos aumenten de manera considerable.
Objetivo: Determinar las lesiones histológicas frecuentes vistas en biopsia renal de pacientes diabéticos con datos de nefropatía diabética tratados en el hospital Luis Vernaza en el año 2014.
Materiales y Métodos: Estudio retrospectivo, descriptivo y de observación indirecta; en el cual se analizaron las historias clínicas y biopsias de todos los pacientes diabéticos valorados por el servicio de nefrología con datos nefropatía diabética, se recabaron variables de importancia epidemiológica como edad, sexo, entre otras; una vez obtenida la información se realizó el análisis de los resultados mediante la elaboración de cuadros estadísticos, y gráficos, para lo cual se utilizó el programa Excel 2010.
Resultados: Existieron 587 diabéticos hospitalizados de las cuales 298 tenían nefropatía y de estos se tomó una muestra de 100, siendo mayor el número de varones; la edad de 71 -79 años, y la procedencia de la zona urbano-marginal. La lesión histológica más frecuente fue la Glomeruloesclerosis difusa seguida de la nodular. La deficiencia de la función renal según el IFG se estableció en 15 – 29 ml/min/1,73 m2 que corresponde al Estadio III de ERC. El grupo etario de entre 80 – 95 fue la que más requirió tratamiento sustitutivo.
Conclusiones: Existe leve variabilidad en cuanto a la lesiones histológicas de Nefropatía Diabética.
Palabras claves: Histopatología, biopsia, nefropatía, diabetes, complicaciones, filtración glomerular.
Introduction: Diabetes and chronic complication more common as Diabetic Nephropathy happen to be a serious public health and q latter is a common cause of terminal which leads to suggest specialized as dialysis treatment chronic kidney disease, be it peritoneal or hemodialysis, which gives as a result the rate of morbidity, mortality and economic costs increase considerably. Objective: Determine common histological lesions seen on renal biopsy data diabetic patients with diabetic nephropathy treated at the hospital Luis Vernaza in 2014. Materials and Methods: A retrospective, descriptive study of indirect observation; in which the medical records and biopsies of all diabetic patients assessed by the nephrology department with diabetic nephropathy data were analyzed epidemiologically important variables such as age, sex were collected, among others; Once the data analysis of the results was performed by developing statistical tables and graphs, for which the Excel 2010 program was used. Results: There were 587 hospitalized diabetic nephropathy which had 298 and of these a sample of 100 was taken, being greater the number of men; the age of 71 -79 years, and the origin of the urban fringe area. The most common histological injury was followed by diffuse nodular glomerulosclerosis. The impairment of renal function according to the IFG was set at 15 to 29 ml / min / 1.73 m2 which corresponds to Stage III of ERC. The age group between 80-95 was the most required substitution treatment. Conclusions: Slight variability exists as to the histological lesions of diabetic nephropathy. Key words: histopathology, biopsy, kidney disease, diabetes, complications, glomerular filtration.
Introduction: Diabetes and chronic complication more common as Diabetic Nephropathy happen to be a serious public health and q latter is a common cause of terminal which leads to suggest specialized as dialysis treatment chronic kidney disease, be it peritoneal or hemodialysis, which gives as a result the rate of morbidity, mortality and economic costs increase considerably. Objective: Determine common histological lesions seen on renal biopsy data diabetic patients with diabetic nephropathy treated at the hospital Luis Vernaza in 2014. Materials and Methods: A retrospective, descriptive study of indirect observation; in which the medical records and biopsies of all diabetic patients assessed by the nephrology department with diabetic nephropathy data were analyzed epidemiologically important variables such as age, sex were collected, among others; Once the data analysis of the results was performed by developing statistical tables and graphs, for which the Excel 2010 program was used. Results: There were 587 hospitalized diabetic nephropathy which had 298 and of these a sample of 100 was taken, being greater the number of men; the age of 71 -79 years, and the origin of the urban fringe area. The most common histological injury was followed by diffuse nodular glomerulosclerosis. The impairment of renal function according to the IFG was set at 15 to 29 ml / min / 1.73 m2 which corresponds to Stage III of ERC. The age group between 80-95 was the most required substitution treatment. Conclusions: Slight variability exists as to the histological lesions of diabetic nephropathy. Key words: histopathology, biopsy, kidney disease, diabetes, complications, glomerular filtration.
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Nefropatía diabética, Biopsia, Patología, Epidemiologia descriptiva, Estudios retrospectivos, Hospital Luis Vernaza, Cantón Guayaquil, Ecuador