Correlación entre síntomas clínicos, parámetros bioquímicos, antropométricos y riesgo cardiovascular en pacientes climatéricas
Fecha
2021
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Universidad de Guayaquil. Facultad de Ciencias Médicas. Escuela de Graduados
Resumen
El climaterio representa un período crítico en la vida de las mujeres que marca
un aumento del riesgo de enfermedad cardiovascular, debido a las alteraciones
bioquímicas y morfológicas que se presentan. Los datos sugieren que las
asociaciones de los parámetros de evaluación dependen de la presencia o ausencia
de síntomas. Objetivo: Determinar la correlación entre síntomas clínicos,
parámetros bioquímicos, antropométricos y riesgo cardiovascular en pacientes
climatéricas. Metodología: Estudio cuantitativo, analítico, retrospectivo y
transversal. La unidad de análisis es el hospital de la mujer Alfredo G. Paulson. Se
evaluaron 262 historias clínicas del periodo de 1 de enero a 31 de diciembre del
2019. La muestra estará dividida en grupo de mujeres sintomáticas y asintomáticas
(grupo control). Resultados: Del total de expedientes analizados, el 66% y 34%
fueron de riesgo cardiovascular alto y bajo. En el grupo con riesgo CV alto
predominaron pacientes > 60 años (72%) y con escolaridad de primaria (24%) y
secundaria (53%). Según la escala MRS, en el grupo con riesgo CV alto fueron más
frecuentes los sofocos (89%), molestias al corazón (62%), problemas de sueño
(55%) y problemas musculares (71%). El grupo de riesgo CV alto presentó valores
promedios más elevados de presión arterial sistólica (148,26 mmHg), presión
arterial diastólica (88,32 mmHg) y de presión arterial media (114,45 mmHg),
glucosa (113,68 mg/dL), hemoglobina glucosilada (6,14%), HDL (38,57 mg/dL),
LDL (109,22 mg/dL), triglicéridos (149,88 mg/dL), colesterol total (199,54
mg/dL), T3 (1,04 nmol/L) y T4 (63,74 nmol/L). Conclusión: Existen diferencias
estadísticamente significativas de la escala MRS, PAS, PAD, PAM, glucosa,
HbA1c, T4, HDL, LDL, TG y colesterol, IMC y perímetro abdominal entre el grupo
de alto y bajo riesgo CV.
The climacteric represents a critical period in the life of women that marks an increased risk of cardiovascular disease, due to the biochemical and morphological alterations that occur. The data suggest that the associations of the endpoints depend on the presence or absence of symptoms. Objective: To determine the correlation between clinical symptoms, biochemical and anthropometric parameters and cardiovascular risk in climacteric patients. Methodology: Quantitative, analytical, retrospective and cross-sectional study. The unit of analysis is the Alfredo G. Paulson Women's Hospital. 262 medical records were evaluated for the period from January 1 to December 31, 2019. The sample will be divided into a group of symptomatic and asymptomatic women (control group). Results: Of the total of records analyzed, 66% and 34% were of high and low cardiovascular risk. In the group with high CV risk, patients> 60 years (72%) and with primary (24%) and secondary education (53%) predominated. According to the MRS scale, in the group with high CV risk, hot flashes (89%), heart discomfort (62%), sleep problems (55%) and muscle problems (71%) were more frequent. The high CV risk group presented higher mean values of systolic blood pressure (148.26 mmHg), diastolic blood pressure (88.32 mmHg) and mean arterial pressure (114.45 mmHg), glucose (113.68 mg / dL), glycated hemoglobin (6.14%), HDL (38.57 mg / dL), LDL (109.22 mg / dL), triglycerides (149.88 mg / dL), total cholesterol (199.54 mg / dL), T3 (1.04 nmol / L) and T4 (63.74 nmol / L). Conclusion: There are statistically significant differences in the MRS, SBP, DBP, MAP, glucose, HbA1c, T4, HDL, LDL, TG and cholesterol, BMI and abdominal circumference between the high and low CV risk group.
The climacteric represents a critical period in the life of women that marks an increased risk of cardiovascular disease, due to the biochemical and morphological alterations that occur. The data suggest that the associations of the endpoints depend on the presence or absence of symptoms. Objective: To determine the correlation between clinical symptoms, biochemical and anthropometric parameters and cardiovascular risk in climacteric patients. Methodology: Quantitative, analytical, retrospective and cross-sectional study. The unit of analysis is the Alfredo G. Paulson Women's Hospital. 262 medical records were evaluated for the period from January 1 to December 31, 2019. The sample will be divided into a group of symptomatic and asymptomatic women (control group). Results: Of the total of records analyzed, 66% and 34% were of high and low cardiovascular risk. In the group with high CV risk, patients> 60 years (72%) and with primary (24%) and secondary education (53%) predominated. According to the MRS scale, in the group with high CV risk, hot flashes (89%), heart discomfort (62%), sleep problems (55%) and muscle problems (71%) were more frequent. The high CV risk group presented higher mean values of systolic blood pressure (148.26 mmHg), diastolic blood pressure (88.32 mmHg) and mean arterial pressure (114.45 mmHg), glucose (113.68 mg / dL), glycated hemoglobin (6.14%), HDL (38.57 mg / dL), LDL (109.22 mg / dL), triglycerides (149.88 mg / dL), total cholesterol (199.54 mg / dL), T3 (1.04 nmol / L) and T4 (63.74 nmol / L). Conclusion: There are statistically significant differences in the MRS, SBP, DBP, MAP, glucose, HbA1c, T4, HDL, LDL, TG and cholesterol, BMI and abdominal circumference between the high and low CV risk group.
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CLIMATERIO, FACTORES DE RIESGO, MENOPAUSIA, PRESION ARTERIAL, HOSPITAL DE LA MUJER ALFREDO G. PAULSON, CANTON GUAYAQUIL, ECUADOR