Asociación entre el síndrome metabólico y el cáncer de mama en mujeres posmenopáusicas
Fecha
2022
Título de la revista
ISSN de la revista
Título del volumen
Editor
Universidad de Guayaquil. Facultad de Ciencias Médicas. Escuela de Graduados
Resumen
Introducción. El factor de riesgo más importante para el desarrollo del síndrome
metabólico (SM) es la obesidad, un estado pro inflamatorio con alteraciones sistémicas y
locales vinculadas al crecimiento tumoral, siendo un determinante en el desarrollo del
cáncer de mama en la posmenopausia, en su pronóstico y en la eficacia del tratamiento.
Objetivo. Determinar la asociación entre el SM y el Cáncer de Mama en mujeres
posmenopáusicas. Materiales y métodos. El estudio fue de diseño cuantitativo de tipo
observacional, descriptivo, correlacional, retrospectivo y de corte transversal. La población
de este estudio fue constituida por mujeres que acuden al Instituto Oncológico Nacional
“Dr. Juan Tanca Marengo”, ya sea por diagnóstico de cáncer de mama o patología benigna,
en el año 2019. Resultados. Se aplicó la prueba estadística Chi cuadrado para contrastar la
hipótesis nula si las variables grupo etario según condición de enfermedad es
independiente del SM obteniéndose diferencias estadísticamente significativas.
Conclusiones. Existe asociación entre el SM y el cáncer de mama en mujeres
posmenopáusicas, por lo que se debe considerar la salud metabólica como un factor de
riesgo clínicamente relevante y modificable para el desarrollo del cáncer. En pacientes
posmenopáusicas con criterios de SM, la detección rutinaria de cáncer de mama ayuda a
detectarlo en etapa temprana. Son necesarios más estudios para predecir el riesgo de
recurrencia del cáncer y mortalidad.
Introduction. The main risk factor for metabolic syndrome (MS) is obesity, a proinflammatory state with systemic and local alterations linked to tumor growth, being a determinant in the development of postmenopausal breast cancer, its prognosis, and the efficacy of treatment. Purpose. The present study aimed to determine the relationship between MS and Breast Cancer in postmenopausal women. Materials and methods. The study had a quantitative, observational, descriptive, correlational, retrospective, and crosssectional design. The population of this study was made up of women who attend the National Oncology Institute “Dr. Juan Tanca Marengo,” either by a diagnosis of breast cancer or by screening with benign pathology in 2019. Results. The chi-square statistical test was applied to contrast the null hypothesis if the variable age group according to disease condition is independent of MS, obtaining statistically significant differences. Conclusions. There is an association between MS and breast cancer in postmenopausal women, so metabolic health should be considered a relevant and modifiable risk factor for cancer development. In postmenopausal patients with MS criteria, routine screening for breast cancer helps detect it early. More studies are needed to predict the risk of cancer recurrence and mortality
Introduction. The main risk factor for metabolic syndrome (MS) is obesity, a proinflammatory state with systemic and local alterations linked to tumor growth, being a determinant in the development of postmenopausal breast cancer, its prognosis, and the efficacy of treatment. Purpose. The present study aimed to determine the relationship between MS and Breast Cancer in postmenopausal women. Materials and methods. The study had a quantitative, observational, descriptive, correlational, retrospective, and crosssectional design. The population of this study was made up of women who attend the National Oncology Institute “Dr. Juan Tanca Marengo,” either by a diagnosis of breast cancer or by screening with benign pathology in 2019. Results. The chi-square statistical test was applied to contrast the null hypothesis if the variable age group according to disease condition is independent of MS, obtaining statistically significant differences. Conclusions. There is an association between MS and breast cancer in postmenopausal women, so metabolic health should be considered a relevant and modifiable risk factor for cancer development. In postmenopausal patients with MS criteria, routine screening for breast cancer helps detect it early. More studies are needed to predict the risk of cancer recurrence and mortality
Descripción
PDF
Palabras clave
Posmenopausia, Neoplasias de la mama, Estudio descriptivo, Factores de riesgo, Obesidad, Hospital Solca de Guayaquil, Cantón Guayaquil, Ecuador