Características clínicas de la miomatosis uterina y sus implicaciones en la salud reproductiva
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2022
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Universidad de Guayaquil. Facultad de Ciencias Médicas. Carrera de Medicina
Resumen
Los miomas uterinos también denominados fibromiomas o leiomiomas, son tumores benignos únicos o múltiples, que derivan de miocitos presentes en el miometrio con una estructura histológica monoclonal, formados por matriz extracelular rodeada por una caja de tejido conectivo y fibras musculares. Tienen una prevalencia entre el 30% y 40% en mujeres de edad reproductiva y afectan hasta el 70% de las mujeres mayores de 30 años, siendo más frecuentes en el 80% de mujeres de raza negra y 50% de raza blanca. Se estima que la miomatosis uterina se asocia al embarazo con una frecuencia del 1 al 4%, cuyas complicaciones se encuentran en relación al tamaño, localización y numero de los miomaS. El 80% de los miomas uterinos presentes en el embarazo permanecen del mismo tamaño o se vuelven más pequeños, dependiendo de la edad gestacional y de la influencia de los estrógenos, ya que dicha hormona predomina en el embarazo, es así, que un tercio de los casos evidencian crecimiento en el primer trimestre de gestación. La American Fertility Society Guideline for Practice determinó que la miomatosis uterina se asocia en un 5 y 10% con casos de infertilidad, sin embargo, se puede asociar como único factor entre 2 y 3% de los casos reportados; es así, que toma en cuenta a los resultados de fertilidad posterior a una miomectomía para establecer su asociación con la infertilidad
Uterine fibroids, also called fibromyomas or leiomyomas, are single or multiple benign tumors that derive from myocytes present in the myometrium with a monoclonal histological structure, formed by extracellular matrix surrounded by a connective tissue box and muscle fibers. They have a prevalence between 30% and 40% in women of reproductive age and affect up to 70% of women over 30 years of age, being more frequent in 80% of black women and 50% of white women. It is estimated that uterine myomatosis is associated with pregnancy with a frequency of 1 to 4%, whose complications are related to the size, location and number of fibroids. 80% of uterine fibroids present in pregnancy remain the same size or become smaller, depending on gestational age and the influence of estrogen, since this hormone predominates in pregnancy, thus, a third of the cases show growth in the first trimester of pregnancy. The American Fertility Society Guideline for Practice determined that uterine myomatosis is associated in 5 and 10% with cases of infertility, however, it can be associated as the only factor between 2 and 3% of reported cases; Thus, it takes into account the results of fertility after a myomectomy to establish its association with infertility
Uterine fibroids, also called fibromyomas or leiomyomas, are single or multiple benign tumors that derive from myocytes present in the myometrium with a monoclonal histological structure, formed by extracellular matrix surrounded by a connective tissue box and muscle fibers. They have a prevalence between 30% and 40% in women of reproductive age and affect up to 70% of women over 30 years of age, being more frequent in 80% of black women and 50% of white women. It is estimated that uterine myomatosis is associated with pregnancy with a frequency of 1 to 4%, whose complications are related to the size, location and number of fibroids. 80% of uterine fibroids present in pregnancy remain the same size or become smaller, depending on gestational age and the influence of estrogen, since this hormone predominates in pregnancy, thus, a third of the cases show growth in the first trimester of pregnancy. The American Fertility Society Guideline for Practice determined that uterine myomatosis is associated in 5 and 10% with cases of infertility, however, it can be associated as the only factor between 2 and 3% of reported cases; Thus, it takes into account the results of fertility after a myomectomy to establish its association with infertility
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MIOMAS UTERINOS, SALUD REPRODUCTIVA, EPIDEMIOLOGIA ANALITICA, ESTUDIOS PROSPECTIVOS, HOSPITAL BASICO IESS DURAN, CANTON DURAN, ECUADOR