Inmunocromatografía y VDRL como prueba de tamizaje para diagnóstico de Treponema Pallidum (Sífilis).
Fecha
2014
Autores
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Editor
Universidad de Guayaquil. Facultad Piloto de Odontología. Escuela de Postgrado "Dr. José Apolo Pineda".
Resumen
El presente estudio se enfoca en la evaluación de la técnica
inmunocromatográfica como test de tamizaje para la enfermedad
Sífilis, en alumnos de 16 a 18 años de colegios de la ciudad de
Guayaquil que acudieron al Instituto Nacional de Higiene y Medicina
Tropical “Leopoldo Izquieta Pérez”. Esta investigación sigue a una
realizada por la autora previamente, relacionada con la determinación
de la prevalencia de anticuerpos contra Treponema pallidum en la
misma población. La técnica inmunocromatográfica se perfila como
una prueba rápida, sencilla, sin necesidad de equipamiento
sofisticado, de bajo costo, que fácilmente cumple con las
características para su utilización como técnica de screening. Su
desempeño técnico acerca de la validez de los resultados
(sensibilidad, especificidad, valor predictivo positivo y negativo) es
similar al VDRL. Sin embargo, en cuanto a la confiabilidad o
variabilidad, la técnica inmunocromatográfica se muestra como un
ensayo de mayor eficiencia con el 100% de concordancia.
This study focuses on evaluating the immunochromatographic technique as a screening test for syphilis disease, in students who are 16 to 18 years old and assist regularly at schools in the city of Guayaquil and who attended in the National Institute of Hygiene and Tropical Medicine "Leopoldo Pérez Izquieta" . This research follows a previously conducted by the author related to the determination of the prevalence of antibodies against Treponema pallidum in the same population. The immunochromatographic technique is emerging as a fast, simple, without sophisticated test equipment, low cost; it’s easily meets the characteristics for use as a screening technique. Its technical performance on the validity of the results (sensitivity, specificity, positive and negative predictive value) is similar to VDRL. However, as to the reliability or variability, immunochromatographic technique is shown as a more efficient test with 100 % concordance.
This study focuses on evaluating the immunochromatographic technique as a screening test for syphilis disease, in students who are 16 to 18 years old and assist regularly at schools in the city of Guayaquil and who attended in the National Institute of Hygiene and Tropical Medicine "Leopoldo Pérez Izquieta" . This research follows a previously conducted by the author related to the determination of the prevalence of antibodies against Treponema pallidum in the same population. The immunochromatographic technique is emerging as a fast, simple, without sophisticated test equipment, low cost; it’s easily meets the characteristics for use as a screening technique. Its technical performance on the validity of the results (sensitivity, specificity, positive and negative predictive value) is similar to VDRL. However, as to the reliability or variability, immunochromatographic technique is shown as a more efficient test with 100 % concordance.
Descripción
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Palabras clave
SIFILIS, EPIDEMIOLOGIA, TAMIZAJE