Plaquetopenia como predictor de muerte en pacientes graves internados en el Hospital Luis Vernaza
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2015
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Universidad de Guayaquil. Facultad de Ciencias Médicas. Escuela de Graduados
Resumen
Antecedentes: Existe una búsqueda de marcadores para establecer pronóstico en pacientes hospitalizados ya que los existentes suelen implicar dificultades técnicas y de costos por lo que no siempre se pueden realizar. Las plaquetas son importantes en la fisiología humana, cualidades que se podrían utilizar para establecer el pronóstico en estos pacientes. Metodología: Con el objetivo de determinar si la plaquetopenia podía pronosticar la muerte en pacientes graves en el hospital “Luis Vernaza” se realizó un estudio caso control en el que se incorporaran pacientes graves que fueron ingresados en hospital Luis Vernaza entre el 1 de enero al 31 de diciembre de 2011. Se escogieron 31 pacientes en los que se evidenció plaquetas disminuidas y 32 pacientes en el grupo que no lo desarrolló. Se compararon utilizando la prueba de Chi2 y la prueba exacta de Fisher, considerándose significativos valores de P 0,05. Resultado: La edad, el tipo de patología no tuvo diferencias estadísticamente significativas entre los grupos (P< 0.01). La presencia de muerte entre pacientes con plaquetopenia fue superior a la de los vivos con conteo de plaquetas por debajo de 150.000 (35,48% vs 12,50%) lo cual no configuró diferencia estadísticamente significativa (P< 0.05). Existe una relación de aproximadamente 4:1 muertes en los pacientes que tienen (OR 3.89) plaquetopenia en relación a si no la tienen. Existe también un aumento del riesgo directo de morir (RR 1,7) Conclusiones: La presencia de plaquetopenia incrementa el riesgo indirecto y directo de muerte en pacientes hospitalizados.
There is a search for markers for determining prognosis in hospitalized patients as existing techniques usually involve difficulties and costs which can not always be performed. Platelets are important in human physiology, qualities that could be used to establish the prognosis in these patients. Methodology: In order to determine whether platelets could predicts death in critically ill patients in the Luis Vernaza hospital a case control study in which critically ill patients who were admitted to this institution from 1 January to 31 incorporated was performed December 2011. 31 patients in whom decreased platelets and 32 patients was observed in the group that did not developed were chosen. Were compared using the Chi2 test and Fisher 's exact test, considering significant at P 0.05. Results: The age, type of disease had no statistically significant differences between groups (P <0.01). The presence of death in patients with thrombocytopenia was higher than that of living with platelet count below 150,000 (35.48% vs 12.50 %), which set no statistically significant difference (P < 0.05). There is a ratio of about 4:1 deaths in patients with (OR 3.89) compared to platelets if they do not. There is also an increased risk of dying Direct (RR 1.7) Conclusions: The presence of thrombocytopenia increases the indirect and direct risk of death in patients with thrombocytopenia
There is a search for markers for determining prognosis in hospitalized patients as existing techniques usually involve difficulties and costs which can not always be performed. Platelets are important in human physiology, qualities that could be used to establish the prognosis in these patients. Methodology: In order to determine whether platelets could predicts death in critically ill patients in the Luis Vernaza hospital a case control study in which critically ill patients who were admitted to this institution from 1 January to 31 incorporated was performed December 2011. 31 patients in whom decreased platelets and 32 patients was observed in the group that did not developed were chosen. Were compared using the Chi2 test and Fisher 's exact test, considering significant at P 0.05. Results: The age, type of disease had no statistically significant differences between groups (P <0.01). The presence of death in patients with thrombocytopenia was higher than that of living with platelet count below 150,000 (35.48% vs 12.50 %), which set no statistically significant difference (P < 0.05). There is a ratio of about 4:1 deaths in patients with (OR 3.89) compared to platelets if they do not. There is also an increased risk of dying Direct (RR 1.7) Conclusions: The presence of thrombocytopenia increases the indirect and direct risk of death in patients with thrombocytopenia
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Trombocitopenia, Pronóstico, Hospital Luis Vernaza, Cantón Guayaquil, Ecuador