Factores de riesgo asociados a infección intrahospitalaria por bacterias productoras de carbapenemasas, estudio a realizar en el Hospital de Especialidades Dr. Abel Gilbert Pontón período 2014-2015
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2016
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Universidad de Guayaquil. Facultad de Ciencias Médicas. Carrera de Medicina
Resumen
La aparición de resistencia bacteriana a los diversos grupos de antibióticos, constituye un factor relevante que dificulta el correcto accionar del personal de salud ante infecciones que en el pasado pudieron resolverse sin problemas. Este fenómeno presentado desde el origen propio de los antibióticos, ha venido ganando mayor importancia en el transcurso del tiempo. A la fecha, lo más preocupantes, el surgimiento de bacterias capaces de producir carbapenemasas, que son enzimas con el potencial de hidrolizar los carbapenemicos (imipenem, meropenem, ertapenem y doripenem), consiguiendo así inactivar prácticamente al último escalón terapéutico frente a microorganismos gramnegativos multirresistentes. Dejando de esta forma al personal de salud literalmente sin armas para combatir esta nueva amenaza. Ahí la importancia de identificar los factores que predisponen a la adquisición intrahospitalaria de infecciones por este tipo de gérmenes, para mediante ello poder realizar una correcta vigilancia y control que permita mejorar la seguridad de los pacientes y disminuir los riesgos de complicaciones de los mismos durante su estancia hospitalaria.
The emergence of bacterial resistance to various groups of antibiotics, is a relevant factor that hinders the proper actions of health personnel to infections in the past could be solved without problems. This phenomenon presented from the very origin of antibiotics, has been gaining importance in the course of time. To date, most troubling, the emergence of bacteria capable of producing carbapenemases, which are enzymes with the potential to hydrolyze carbapenems (imipenem, meropenem, ertapenem and doripenem), thus inactivating virtually the last therapeutic step against multiresistant gram-negative organisms. Thereby leaving health personnel literally no weapons to fight this new threat. Hence the importance of identifying the factors that predispose to nosocomial infections such germs, to thereby be able to perform proper monitoring and control to enable improve patient safety and reduce the risks of complications thereof during hospital stay.
The emergence of bacterial resistance to various groups of antibiotics, is a relevant factor that hinders the proper actions of health personnel to infections in the past could be solved without problems. This phenomenon presented from the very origin of antibiotics, has been gaining importance in the course of time. To date, most troubling, the emergence of bacteria capable of producing carbapenemases, which are enzymes with the potential to hydrolyze carbapenems (imipenem, meropenem, ertapenem and doripenem), thus inactivating virtually the last therapeutic step against multiresistant gram-negative organisms. Thereby leaving health personnel literally no weapons to fight this new threat. Hence the importance of identifying the factors that predispose to nosocomial infections such germs, to thereby be able to perform proper monitoring and control to enable improve patient safety and reduce the risks of complications thereof during hospital stay.
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Infección hospitalaria, Enterobacteriaceae Resistentes a los Carbapenémicos, Hospital de Especialidades Guayaquil Dr. Abel Gilbert Pontón, Cantón Guayaquil, Ecuador, Epidemiología analítica, Epidemiología descriptiva