Suplementación de vitamina A en tratamiento standard de infecciones respiratorias agudas de 300 niños de 6 meses a 7 años, Hospital de Niños León Becerra de Guayaquil
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2010
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Universidad de Guayaquil. Facultad de Ciencias Médicas. Escuela de Graduados
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Las Infecciones Respiratorias Agudas (IRA) representan uno de los principales motivos de consulta en atención primaria en todo el mundo, principalmente de menores de 7 años de edad. Aún cuando la mayoría de las IRA son autolimitadas, los errores diagnósticos y terapéuticos representan un problema por el uso excesivo e inadecuado de antimicrobianos, lo cual ha dado origen a resistencia bacteriana y desperdicio de medicamentos. Las IRA constituyen un variado grupo de enfermedades que afectan diferentes partes de las vías respiratorias y cuyas manifestaciones son similares; además es importante tener en cuenta que los músculos cardiaco y respiratorios son los únicos que funcionan constantemente sin períodos de descanso, por lo que una depleción nutricional o un estado de malnutrición puede tener un efecto agravante sobre los pacientes con enfermedades respiratorias. Se sabe que la infección respiratoria aguda afecta y, a su vez, es afectada por el estado nutricional del paciente; además que los micronutrientes tienen una estrecha relación con el buen funcionamiento del sistema inmune. Por lo tanto, se ha hallado que la administración de mega dosis de vitamina A reduce la mortalidad y gravedad de las infecciones respiratorias en niños(11, 16). Por consiguiente, este estudio experimental, prospectivo, longitudinal y comparativo; se realizó con la finalidad de evaluar la efectividad del tratamiento complementario de vitamina A en niños hospitalizados que padecen procesos respiratorios agudos.
Acute Respiratory Infections (ARI) represent one of the main reasons for consultation in primary care worldwide, mainly children under 7 years of age. Although most of the ARI are selflimited, diagnostic and therapeutic errors represent a problem of excessive and inappropriate use of antimicrobials, which has led to bacterial resistance and drug wastage. The ARI are a diverse group of diseases that affect different parts of the airways and whose manifestations are similar, it is also important to note that cardiac and respiratory muscles are the ones that run continuously without rest periods, so a depletion nutritional status or malnutrition can have an aggravating effect on patients with respiratory diseases. It is known that acute respiratory infection affects and, in turn, is affected by the patient's nutritional status; further that the micronutrients have a close relationship with the proper functioning of the immune system. Therefore, it is found that the administration of mega doses of vitamin A reduces mortality and severity of respiratory infections in children (11, 16). Therefore, this experimental study, prospective, longitudinal, comparative study was carried out, in order to evaluate the effectiveness of adjunct of vitamin A in hospitalized children suffering from acute respiratory processes
Acute Respiratory Infections (ARI) represent one of the main reasons for consultation in primary care worldwide, mainly children under 7 years of age. Although most of the ARI are selflimited, diagnostic and therapeutic errors represent a problem of excessive and inappropriate use of antimicrobials, which has led to bacterial resistance and drug wastage. The ARI are a diverse group of diseases that affect different parts of the airways and whose manifestations are similar, it is also important to note that cardiac and respiratory muscles are the ones that run continuously without rest periods, so a depletion nutritional status or malnutrition can have an aggravating effect on patients with respiratory diseases. It is known that acute respiratory infection affects and, in turn, is affected by the patient's nutritional status; further that the micronutrients have a close relationship with the proper functioning of the immune system. Therefore, it is found that the administration of mega doses of vitamin A reduces mortality and severity of respiratory infections in children (11, 16). Therefore, this experimental study, prospective, longitudinal, comparative study was carried out, in order to evaluate the effectiveness of adjunct of vitamin A in hospitalized children suffering from acute respiratory processes
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Infecciones del sistema respiratorio, Vitamina A, Pediatría, MIcronutrientes, Epidemiología descriptiva, Hospital León Becerra de Guayaquil, Cantón Guayaquil, Ecuador