Correlación insulina y metformina en el tratamiento de diabetes gestacional, resultante obstétrica y neonatal Hospital de la Mujer Alfredo G. Paulson enero 2017-enero 2018
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2018
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Universidad de Guayaquil. Facultad de Ciencias Médicas. Escuela de Graduados
Resumen
El presente trabajo de investigación, compara los resultantes obstétricos y neonatales en mujeres con diabetes gestacional tratadas con Metformina, en comparación con Insulina, en el Hospital de la Mujer Alfredo G Paulson, de la ciudad de Guayaquil, en el período Enero 2017 a Enero 2018. Por su diseño y tipo metodológico se estableció un estudio: Descriptivo, Correlacional, no experimental de corte transversal. Para lo cual se midieron variables como: Valores de glicemia pre y pos tratamiento, resultantes obstétricos y neonatales. En la validación de prueba de hipótesis, se usaron (IC 95%) e índice de error del 5%. La población de estudio se caracterizó por presentar asimetría con un (42.5%), de pacientes tratadas con Metformina y (57.5%) con Insulina, de las complicaciones obstétricas destacan: Amenaza de parto pre-termino (17 casos), ruptura prematura de membranas (9 casos), infección del tracto urinario (9 casos), trabajo de parto pre-termino (15 casos), polihidramnios (15 casos), y aborto (4 casos), con una prueba de (Chi cuadrado de asociación) equivalente a 0.000. De las complicaciones neonatales se observó que: El distrés respiratorio del recién nacido (40 casos), la hipoglicemia neonatal (11 casos), hiperbilirrubinemia (9 casos), son las patologías asociadas a tratamiento farmacológico para control de diabetes gestacional. En cuanto al control de glicemia entre ambas drogas hubo un adecuado control sérico con ambas drogas, con una prueba T de Student de .000. En conclusión se acepta la hipótesis afirmativa la cual postula: El tratamiento con metformina tiene igual resultante materno y neonatal comparado con insulina, en mujeres con diagnóstico de diabetes gestacional atendidas en el Hospital de la Mujer Alfredo G Paulson, durante el período Enero 2017 a Enero 2018.
This research paper compares the obstetric and neonatal outcomes in women with gestational diabetes, treated with Metformin compared to Insulin, in the Alfredo G Paulson woman's hospital in the city of Guayaquil, from January 2017 to January 2018, Its design and methodological type was established in a study: Descriptive, Correlational, nonexperimental cross-sectional. For which variables were measured as: glycemia values before and after treatment, resulting obstetric and neonatal. For validation of the hypothesis test, (95% CI) and 5% error rate were used. The study population was characterized by asymmetry with one (42.5%) of patients treated with Metformin and (57.5%) with Insulin, the obstetric complications include: Threat of pre-term delivery (17 cases), premature rupture of membranes (9 cases), urinary tract infection (9 cases), pre-term labor (15 cases), polyhydramnios, (15 cases), and abortion (4 cases), with a (Chi-square of association) test equivalent to 0.000. Of the neonatal complications it was observed that: Newborn respiratory distress (40 cases), neonatal hypoglycemia (11 cases), hyperbilirubinemia (9 cases), are the pathologies associated with pharmacological treatment for gestational diabetes control. As for the control of glycemia between both drugs, there was an adequate serum control with both drugs, with a Student's T test of .000. In conclusion, the affirmative hypothesis is accepted, which postulates: Metformin treatment has the same resulting maternal and neonatal compared to insulin in women diagnosed with gestational diabetes attended at the Alfredo G Paulson Women's Hospital during the period January 2017 to January 2018.
This research paper compares the obstetric and neonatal outcomes in women with gestational diabetes, treated with Metformin compared to Insulin, in the Alfredo G Paulson woman's hospital in the city of Guayaquil, from January 2017 to January 2018, Its design and methodological type was established in a study: Descriptive, Correlational, nonexperimental cross-sectional. For which variables were measured as: glycemia values before and after treatment, resulting obstetric and neonatal. For validation of the hypothesis test, (95% CI) and 5% error rate were used. The study population was characterized by asymmetry with one (42.5%) of patients treated with Metformin and (57.5%) with Insulin, the obstetric complications include: Threat of pre-term delivery (17 cases), premature rupture of membranes (9 cases), urinary tract infection (9 cases), pre-term labor (15 cases), polyhydramnios, (15 cases), and abortion (4 cases), with a (Chi-square of association) test equivalent to 0.000. Of the neonatal complications it was observed that: Newborn respiratory distress (40 cases), neonatal hypoglycemia (11 cases), hyperbilirubinemia (9 cases), are the pathologies associated with pharmacological treatment for gestational diabetes control. As for the control of glycemia between both drugs, there was an adequate serum control with both drugs, with a Student's T test of .000. In conclusion, the affirmative hypothesis is accepted, which postulates: Metformin treatment has the same resulting maternal and neonatal compared to insulin in women diagnosed with gestational diabetes attended at the Alfredo G Paulson Women's Hospital during the period January 2017 to January 2018.
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Diabetes gestacional, Metformina, Insulina, Epidemiología descriptiva, Hospital de la Mujer Alfredo G. Paulson, Cantón Guayaquil, Ecuador, Resultante neonatal