Correlación ecográfica e histopatológica de lesiones mamarias BI-RADS 4 y 5 en el diagnóstico de carcinoma ductal in situ
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2021
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Universidad de Guayaquil. Facultad de Ciencias Médicas. Escuela de Graduados
Resumen
El carcinoma ductal in situ de mama (CDIS), es una lesión prevalente en mujeres mayores de 40 años. El presente estudio correlaciona los hallazgos BI-RADS 4 y 5 con resultados histopatologicos mediante biopsia TRUCUT para el diagnóstico de (CDIS) en mujeres mayores de 40 años atendidas en el servicio de imagenología del hospital “Dr. Teodoro Maldonado Carbo”. Para ello se planteó un estudio de tipo: Analítico, retrospectivo, no experimental, de corte transversal. Para la validez estadística se usó prueba Chi cuadrado con un (IC) del 95% e IR del 5%. Los hallazgos de biopsia demostraron que los CDIS fueron 24 casos para BIRADS IV y 15 casos para BIRADS V. La edad promedio fue 47 años, los factores de riesgo fueron deformidad mamaria (24.77%), tabaquismo (15.60%), recurrencia de nódulos (8.26%) y obesidad (7.34%). Las características ecográficas fueron: Lesión promedio 3.23 cm, irregularidad con un 82.05, márgenes no circunscritos con un 84.62 %, calcificaciones con un 82.05 % y asimetría con un 74.35 %. En cuanto a la ecogenicidad un 58.97 % presentaron un patrón complejo. La sensibilidad del BIRADS fue del 35.0 % con una especificidad del 71.7 % para CDIS, lo que le confirió un valor predictivo positivo con un (VPP) del 61.53 y un (VPN) del 45.78. Mediante Chi cuadrado se correlacionó los hallazgos BI-RADS IV y V con los resultados histopatológicos mediante la biopsia TRUCUT obteniéndose un (p valor) de .013 lo que indica que: Existe una adecuada relación de asociación entre ambos elementos de estudio
Ductal carcinoma in situ of the breast (DCIS) is a prevalent lesion in women over 40 years of age. The present study correlates the BI-RADS 4 and 5 findings with histopathological results using TRUCUT biopsy for the diagnosis of (DCIS) in women over 40 years of age treated in the imaging service of the “Dr. Teodoro Maldonado Carbo ”. For this, a study of the type was proposed: Analytical, retrospective, non-experimental, cross-sectional. For statistical validity, the Chi-square test was used with a (CI) of 95% and IR of 5%. The biopsy findings showed that the DCIS was 24 cases for BIRADS IV and 15 cases for BIRADS V. The average age was 47 years, the risk factors were breast deformity (24.77%), smoking (15.60%), recurrence of nodules ( 8.26%) and obesity (7.34%). The ultrasound characteristics were: Average lesion 3.23 cm, irregularity with 82.05, non-circumscribed margins with 84.62%, calcifications with 82.05% and asymmetry with 74.35%. Regarding echogenicity, 58.97% presented a complex pattern. The sensitivity of the BIRADS was 35.0% with a specificity of 71.7% for DCIS, which gave it a positive predictive value with a (PPV) of 61.53 and a (NPV) of 45.78. By means of Chi square, the BI-RADS IV and V findings were correlated with the histopathological results using the TRUCUT biopsy, obtaining a (p value) of .013, which indicates that: There is an adequate association relationship between both study elements.
Ductal carcinoma in situ of the breast (DCIS) is a prevalent lesion in women over 40 years of age. The present study correlates the BI-RADS 4 and 5 findings with histopathological results using TRUCUT biopsy for the diagnosis of (DCIS) in women over 40 years of age treated in the imaging service of the “Dr. Teodoro Maldonado Carbo ”. For this, a study of the type was proposed: Analytical, retrospective, non-experimental, cross-sectional. For statistical validity, the Chi-square test was used with a (CI) of 95% and IR of 5%. The biopsy findings showed that the DCIS was 24 cases for BIRADS IV and 15 cases for BIRADS V. The average age was 47 years, the risk factors were breast deformity (24.77%), smoking (15.60%), recurrence of nodules ( 8.26%) and obesity (7.34%). The ultrasound characteristics were: Average lesion 3.23 cm, irregularity with 82.05, non-circumscribed margins with 84.62%, calcifications with 82.05% and asymmetry with 74.35%. Regarding echogenicity, 58.97% presented a complex pattern. The sensitivity of the BIRADS was 35.0% with a specificity of 71.7% for DCIS, which gave it a positive predictive value with a (PPV) of 61.53 and a (NPV) of 45.78. By means of Chi square, the BI-RADS IV and V findings were correlated with the histopathological results using the TRUCUT biopsy, obtaining a (p value) of .013, which indicates that: There is an adequate association relationship between both study elements.
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CARCINOMA DUCTAL, ECOGRAFIA, BIOPSIA, HOSPITAL DE ESPECIALIDADES DR. TEODORO MALDONADO CARBO, CANTON GUAYAQUIL, ECUADOR