Hallazgos radiológicos por resonancia magnética en pacientes con alzheimer
Fecha
2023
Autores
Título de la revista
ISSN de la revista
Título del volumen
Editor
Universidad de Guayaquil. Facultad de Ciencias Médicas. Escuela de Graduados
Resumen
Antecedentes: La placenta es un órgano muy importante para el mantenimiento
del feto, sin embargo, aún es controversial si sus características histopatológicas,
se asocian al tipo de resultado perinatal en neonatos pretérminos nacidos de parto
vaginal. Objetivos: Establecer si los hallazgos histopatológicos placentarios se
asocian con el resultado perinatal de los neonatos de partos vaginales pretérminos
espontáneos. Metodología: Se realizó un estudio caso control que incluyó
aleatorizadamente, 100 partos vaginales espontáneos pretérminos, (34 casos de
eventos adversos y 66 casos sin eventos) atendidos en el Hospital Alfredo
G. Paulson en Guayaquil, Ecuador, en el período 1-01-2019 al 30-03-2021. Para el
análisis estadístico se utilizó prueba de chi-cuadrado de homogeneidad, prueba t
de student para muestra independiente y odds ratio. Se consideró significativo un p
< 0.05. Resultados: La vasculitis se asoció a eventos adversos como protección (p
0.006; OR: 0.783, IC95%: 0.634 – 0.966) y < peso (p 0.049). Las microcalcificaciones
se asociaron a > peso (p 0.040) y > edad gestacional (p 0.032). La corioamnionitis
se asoció a < peso en el neonato (p 0.047). El peso placentario se asoció a >
eventos adversos neonatales (p 0.020; OR: 2.635, IC95%: 1.027 – 6.764), > muertes
neonatales (p 0.013; OR: 4.216, IC95%: 1.070 – 16.618), < Apgar a los 10 minutos
(p 0.043), < edad peso (p 0.003) y < edad gestacional (p 0.000). No mostraron
asociación estadística la presencia de congestión vascular, hemorragia y edema
intervelloso, anormalidades del cordón umbilical. Conclusiones: Ciertos hallazgos
histopatológicos placentarios se asocian con el resultado perinatal de neonatos de
partos vaginales pretérminos espontáneos.
Background: The placenta is a very important organ for the maintenance of the fetus; however, it is still controversial whether its histopathological characteristics are associated with the type of perinatal outcome in preterm infants born vaginally. Objectives: To establish whether placental histopathological findings are associated with perinatal outcome of spontaneous preterm birth vaginal. Methodology: A case control study was carried out that randomly included 100 preterm spontaneous vaginal deliveries (34 cases of adverse events and 66 cases without events) attended at the Alfredo G. Paulson Hospital in Guayaquil, Ecuador, in the period 1-01- 2019 to 03-30-2021. For statistical analysis, the chi-square test for homogeneity, student's t-test for independent sample and odds ratio were used. A p < 0.05 was considered significant. Results: Vasculitis was associated with adverse events such as protection (p 0.006; OR: 0.783, 95% CI: 0.634 – 0.966) and <weight (p 0.049). Microcalcifications were associated with > weight (p 0.040) and > gestational age (p 0.032). Chorioamnionitis was associated with <weight in the newborn (p 0.047). Placental weight was associated with > neonatal adverse events (p 0.020; OR: 2.635, 95% CI: 1.027 - 6.764), > neonatal deaths (p 0.013; OR: 4.216, 95% CI: 1.070 - 16.618), < Apgar at 10 minutes (p 0.043), < weight age (p 0.003) and < gestational age (p 0.000). The presence of vascular congestion, hemorrhage and intervillous edema, abnormalities of the umbilical cord did not show statistical association. Conclusions: Certain placental histopathologic findings are associated with perinatal outcome of spontaneous preterm vaginal delivery infants.
Background: The placenta is a very important organ for the maintenance of the fetus; however, it is still controversial whether its histopathological characteristics are associated with the type of perinatal outcome in preterm infants born vaginally. Objectives: To establish whether placental histopathological findings are associated with perinatal outcome of spontaneous preterm birth vaginal. Methodology: A case control study was carried out that randomly included 100 preterm spontaneous vaginal deliveries (34 cases of adverse events and 66 cases without events) attended at the Alfredo G. Paulson Hospital in Guayaquil, Ecuador, in the period 1-01- 2019 to 03-30-2021. For statistical analysis, the chi-square test for homogeneity, student's t-test for independent sample and odds ratio were used. A p < 0.05 was considered significant. Results: Vasculitis was associated with adverse events such as protection (p 0.006; OR: 0.783, 95% CI: 0.634 – 0.966) and <weight (p 0.049). Microcalcifications were associated with > weight (p 0.040) and > gestational age (p 0.032). Chorioamnionitis was associated with <weight in the newborn (p 0.047). Placental weight was associated with > neonatal adverse events (p 0.020; OR: 2.635, 95% CI: 1.027 - 6.764), > neonatal deaths (p 0.013; OR: 4.216, 95% CI: 1.070 - 16.618), < Apgar at 10 minutes (p 0.043), < weight age (p 0.003) and < gestational age (p 0.000). The presence of vascular congestion, hemorrhage and intervillous edema, abnormalities of the umbilical cord did not show statistical association. Conclusions: Certain placental histopathologic findings are associated with perinatal outcome of spontaneous preterm vaginal delivery infants.
Descripción
PDF
Palabras clave
PARTO PRETERMINO, PLACENTA, HISPATOLOGIA, HOSPITAL ALFREDO G. PAULSON, CANTON GUAYAQUIL, ECUADOR