Correlación clínico – Imagenológica de la esteatosis hepática no alcoholica en pacientes adultos no oncológicos
Fecha
2023
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Universidad de Guayaquil. Facultad de Ciencias Médicas. Escuela de Graduados
Resumen
Introducción: La esteatosis hepática es la causa más común de enfermedad crónica
en adultos, que puede ser asintomática, progresar a cirrosis y cáncer. Para su
diagnóstico se utilizan criterios clínicos y diferentes estudios de imagenología,
como la ecografía, tomografía computarizada, y resonancia magnética nuclear.
Materiales y métodos: estudio observacional descriptivo, con una muestra de 125
pacientes diagnosticados de esteatosis hepática no alcohólica sin patología
oncológica. Las variables estudiadas fueron edad, sexo, laboratorio, estado
nutricional y scores clínicos como FIB-4, APRI y el Índice de Esteatosis Hepática.
Los datos fueron tomados de las historias clínicas de los pacientes y analizados con
el programa SPSS mediante estadística descriptiva e inferencial. Se consideró
resultados estadísticamente significativos a los valores de p<0.05.
Resultados: la edad promedio fue 53.39±15 años; predominaron las mujeres y los
pacientes con obesidad 33.6%. El promedio del IMC fue de 26.81 ± 6.10, del índice
FIB-4 1.26±1.25, del índice APRI 0.27±0.24 y del índice de esteatosis hepática
33.37±7.95. El 85.8% de resultados según el índice de esteatosis hepática se
correlacionan con los de imagenología; con el índice FIB-4 y el índice APRI se
observaron grados de fibrosis similares a los reportados en otros estudios. Se
encontró asociación estadísticamente significativa entre el estado nutricional y el
índice de esteatosis hepática, p=0.000.
Conclusiones: existe una buena correlación entre los parámetros clínicos con las
pruebas imagenológicas en la valoración de la esteatosis hepática no alcohólica y
los diferentes grados de fibrosis hepática.
Introduction: Hepatic steatosis is the most common cause of chronic disease in adults, which can be asymptomatic, progress to cirrhosis and cancer. For its diagnosis, clinical criteria and different imaging studies are used, such as ultrasound, computed tomography, and nuclear magnetic resonance. Materials and methods: descriptive observational study, with a sample of 125 patients diagnosed with non-alcoholic hepatic steatosis without oncological pathology. The variables studied were age, sex, laboratory, nutritional status, and clinical scores such as FIB-4, APRI, and the Hepatic Steatosis Index. The data were taken from the patients' medical records and analyzed with the SPSS program using descriptive and inferential statistics. Statistically significant results were considered at values of p<0.05. Results: the average age was 53.39 ± 15 years; women and patients with obesity 33.6% predominated. Mean BMI was 26.81 ± 6.10, FIB-4 index 1.26 ± 1.25, APRI index 0.27 ± 0.24, and hepatic steatosis index 33.37 ± 7.95. 85.8% of the results according to the hepatic steatosis index correlate with those of imaging; with the FIB-4 index and the APRI index, degrees of fibrosis like those reported in other studies were observed. A statistically significant association was found between nutritional status and the hepatic steatosis index, p=0.000. Conclusions: there is a good correlation between the clinical parameters with the imaging tests in the assessment of non-alcoholic fatty liver disease and the different degrees of liver fibrosis.
Introduction: Hepatic steatosis is the most common cause of chronic disease in adults, which can be asymptomatic, progress to cirrhosis and cancer. For its diagnosis, clinical criteria and different imaging studies are used, such as ultrasound, computed tomography, and nuclear magnetic resonance. Materials and methods: descriptive observational study, with a sample of 125 patients diagnosed with non-alcoholic hepatic steatosis without oncological pathology. The variables studied were age, sex, laboratory, nutritional status, and clinical scores such as FIB-4, APRI, and the Hepatic Steatosis Index. The data were taken from the patients' medical records and analyzed with the SPSS program using descriptive and inferential statistics. Statistically significant results were considered at values of p<0.05. Results: the average age was 53.39 ± 15 years; women and patients with obesity 33.6% predominated. Mean BMI was 26.81 ± 6.10, FIB-4 index 1.26 ± 1.25, APRI index 0.27 ± 0.24, and hepatic steatosis index 33.37 ± 7.95. 85.8% of the results according to the hepatic steatosis index correlate with those of imaging; with the FIB-4 index and the APRI index, degrees of fibrosis like those reported in other studies were observed. A statistically significant association was found between nutritional status and the hepatic steatosis index, p=0.000. Conclusions: there is a good correlation between the clinical parameters with the imaging tests in the assessment of non-alcoholic fatty liver disease and the different degrees of liver fibrosis.
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ESTEATOSIS HEPATICA, ALCOHOLISMO, ADULTO, CIRROCIS HEPATICA, HOSPITAL SOLCA DE GUAYAQUIL, CANTON GUAYAQUIL, ECUADOR