Respuesta al tratamiento con hormona de crecimiento en niños con talla baja por deficiencia de hormona de crecimiento
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2021
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Universidad de Guayaquil. Facultad de Ciencias Médicas. Escuela de Graduados
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Antecedentes. La causa de la talla baja en los niños es multifactorial, desde causas medio ambientales, familiares o el fracaso del crecimiento recuperador, así como atribuida a un déficit de hormona de crecimiento y es principalmente en este grupo donde las guías del MSP autorizan el uso de HC, con la finalidad que los niños alcancen una talla acorde a su edad al llegar a la pubertad. Objetivo. Evaluar la respuesta al tratamiento con hormona de crecimiento en niños con diagnóstico de hipopituitarismo. Metodología. Estudio descriptivo retrospectivo. Resultados. Fueron incluidos 12 niños en el estudio, mismos que cumplieron con los criterios de inclusión que se fundamentaron en análisis antropométricos, imágenes, pruebas de laboratorio y que se encontraban al momento con suplementación con hormona de crecimiento, donde el 67 % fueron hombres y 33% mujeres, la edad promedio fue de 8.8 años, la dosis utilizada fue de 0.035mg/kg/día, la ganancia total correspondió una media de 17.75 DE 11.13 y la ganancia anual fue de 6.63cm DE 2.4 en promedio.
Conclusiones La suplementación con hormona de crecimiento presentó una correlación positiva en relación con la ganancia de talla en cm totales, así como en su consideración anual.
Background. The cause of short stature in children is multifactorial, from environmental and family causes or the failure of recovery growth, as well as such attributed to a growth hormone deficiency and it is mainly within this group where the MSP guidelines authorize the use of HC, in order for children to reach a height according to their age upon reaching puberty. Objective. To assess the response to growth hormone treatment in children diagnosed with hypopituitarism. Methodology. Retrospective descriptive study. Results. Twelve children were included in the study, who met the inclusion criteria that were based on anthropometric analysis, images, laboratory tests and who were currently on growth hormone supplementation, where 67% were men and 33% women, the average age was 8.8 years, the dose used was 0.035mg / kg / day, the total gain corresponded to a mean of 17.75 SD 11.13 and the annual gain was 6.63cm SD 2.4 on average . Conclusions Growth hormone supplementation showed a positive correlation in relation to height gain in total centimeters as well as to its annual consideration.
Background. The cause of short stature in children is multifactorial, from environmental and family causes or the failure of recovery growth, as well as such attributed to a growth hormone deficiency and it is mainly within this group where the MSP guidelines authorize the use of HC, in order for children to reach a height according to their age upon reaching puberty. Objective. To assess the response to growth hormone treatment in children diagnosed with hypopituitarism. Methodology. Retrospective descriptive study. Results. Twelve children were included in the study, who met the inclusion criteria that were based on anthropometric analysis, images, laboratory tests and who were currently on growth hormone supplementation, where 67% were men and 33% women, the average age was 8.8 years, the dose used was 0.035mg / kg / day, the total gain corresponded to a mean of 17.75 SD 11.13 and the annual gain was 6.63cm SD 2.4 on average . Conclusions Growth hormone supplementation showed a positive correlation in relation to height gain in total centimeters as well as to its annual consideration.
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HORMONA DEL CRECIMIENTO, TALLA BAJA, ANTROPOMETRIA, HIPOPITUITARISMO, EPIDEMIOLOGIA DESCRIPTIVA, ESTUDIOS RETROSPECTIVOS, REGISTROS MEDICOS, HOSPITAL DEL NIÑO FRANCISCO DE ICAZA BUSTAMANTE, CANTON GUAYAQUIL, ECUADOR