Perfil lipídico en pacientes diabéticos que acuden al Laboratorio Clínico Riera - Milagro
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2016
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Universidad de Guayaquil. Facultad de Ciencias Químicas
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La diabetes mellitus (DM) se reconoce por los organismos líderes en diabetes: Asociación Americana de Diabetes (ADA), Asociación Latinoamericana de Diabetes (ALD), la Federación Internacional de Diabetes (FID), así como la OMS, los Organismos de Salud regionales (Organización Panamericana de la Salud (OPS) y las Federaciones y/o Asociaciones de Diabetes, de diferentes países, como una enfermedad no transmisible (ENT) de alto impacto sobre la salud y economía de los pueblos. Esta constituye un factor de riesgo de las enfermedades cardiovasculares (ECV). Objetivo: Evaluar estado del metabolismo glucolípido de los pacientes con DM tipo 2, que acuden al Laboratorio Clínico Riera, mediante la determinación de los niveles de la concentración en suero de GLU, HbA1c, CT, TG, HDL-c y LDL-c, como indicadores de riesgo para las complicaciones angiopáticas. Materiales y Métodos: Se estudiaron 75 pacientes con DM tipo 2 con 5 o más años de evolución, (30-65 años) a los cuales se les realizaron entrevistas para registrar los datos personales, se determinó los niveles séricos de los analitos estudiados mediantes técnicas enzimáticas colorimétricas, aplicando el control de calidad del laboratorio. Resultados: En la muestra estudiada se observó una tendencia al incremento de niveles séricos de GLU, HbA1c Ctotal, TG y LDL-c, por diferencia de la HDL-c. Estos resultados indican, presencia de riesgos cardiometabólicos, debido a la hiperglicemia y el perfil lipídico proaterogénico detectado en la muestra de estudio. Conclusiones: En la muestra de pacientes existe alto riesgo para la enfermedad ateroesclerótica
Diabetes mellitus (DM) is recognized by leading organizations in diabetes: American Diabetes Association (ADA), Latin American Diabetes Association (ALD), the International Diabetes Federation (IDF) and WHO, Organizations Regional Health (Pan American health Organization (PAHO) and the Federations and / or Associations of Diabetes, from different countries, as a non-communicable disease (NCD) high impact on the health and economy of the people. This is a risk factor the cardiovascular disease (CVD) Objective. to assess the state of glycolipid metabolism of patients with type 2 diabetes who come to Riera Clinical Laboratory, by determining levels of serum concentration of GLU, HbA1c, TC, TG, HDL-c and LDL-c, as risk for complications angiopathic. Materials and Methods. 75 patients with type 2 diabetes were studied with 5 or more years of evolution, (30-65 years) which were conducted interviews to record personal data, serum levels of analytes through studied enzymatic colorimetric techniques, applying quality control laboratory was determined. Results: In the sample studied was observed a tendency to increased serum levels of Glu, C total HbA1c, TG and LDL-c, by difference of HDL-c. These results indicate the presence of cardiometabolic risk due to hyperglycemia and atherogenic lipid profile detected in the study sample. Conclusions: In the sample of patients there is high risk for atherosclerotic disease. Keywords: Diabetes-Metabolism Lipid Atherognic -Profile glycolipid
Diabetes mellitus (DM) is recognized by leading organizations in diabetes: American Diabetes Association (ADA), Latin American Diabetes Association (ALD), the International Diabetes Federation (IDF) and WHO, Organizations Regional Health (Pan American health Organization (PAHO) and the Federations and / or Associations of Diabetes, from different countries, as a non-communicable disease (NCD) high impact on the health and economy of the people. This is a risk factor the cardiovascular disease (CVD) Objective. to assess the state of glycolipid metabolism of patients with type 2 diabetes who come to Riera Clinical Laboratory, by determining levels of serum concentration of GLU, HbA1c, TC, TG, HDL-c and LDL-c, as risk for complications angiopathic. Materials and Methods. 75 patients with type 2 diabetes were studied with 5 or more years of evolution, (30-65 years) which were conducted interviews to record personal data, serum levels of analytes through studied enzymatic colorimetric techniques, applying quality control laboratory was determined. Results: In the sample studied was observed a tendency to increased serum levels of Glu, C total HbA1c, TG and LDL-c, by difference of HDL-c. These results indicate the presence of cardiometabolic risk due to hyperglycemia and atherogenic lipid profile detected in the study sample. Conclusions: In the sample of patients there is high risk for atherosclerotic disease. Keywords: Diabetes-Metabolism Lipid Atherognic -Profile glycolipid
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DIABETES - METABOLISMO GLUCOLÍPIDO, PERFIL LIPÍDICO ATEROGÉNICO