Aspergilosis pulmonar en pacientes con inmunosupresión en el Hospital José Daniel Rodríguez Maridueña período 2015 - 2017
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2018
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Universidad de Guayaquil. Facultad de Ciencias Médicas. Escuela de Medicina
Resumen
Introducción: La Aspergilosis se refiere a la enfermedad causada por una especie de hongo, Aspergillus. Se puede observar una amplia gama de manifestaciones en la infección por este hongo, incluida la enfermedad alérgica, la enfermedad semi invasiva y la invasiva. El diagnóstico de Aspergilosis es dificultoso debido al riesgo de colonización y contaminación y al bajo valor predictivo de los cultivos de muestras respiratorias, fundamentalmente de esputo
Metodología: El objetivo de este proyecto de investigación es Determinar la correlación clínica entre la presencia de aspergilosis pulmonar en pacientes inmunocomprometidos en el hospital de Infectología Dr. Daniel Rodríguez Maridueña, Se estableció un estudio retrospectivo, observacional y descriptivo durante el período 2015 al 2017, el universo escogido fueron pacientes atendidos en el área de emergencia y hospitalización del Hospital Daniel Rodríguez Maridueña, la muestra fueron 65 pacientes que presentaron varias formas clínicas de la aspergilosis pulmonar.
Resultados: Se observó mayor incidencia de aspergilosis en pacientes entre 26 a 37 años correspondiendo el 36,9% del total de pacientes de la
XVII
muestra tomada. Estudio se encontró una mayor correlación de pacientes con VIH/SIDA y la presencia de Aspergilosis en varias de sus formas; los pacientes con VIH/SIDA representaron un 46,2% con un total de 30 pacientes de los 65 de la muestra tomada. Las formas de presentación clínica de la Aspergilosis hallamos que la forma de Aspergilosis Pulmonar Invasiva presentó mayor incidencia con 25 casos registrados
Palabras clave: VIH, Aspergilosis pulmonar, Semi Invasiva, Invasiva, Aspergiloma, Nódulos, Asmas bronquial, Neutropenia, Tuberculosis
Introduction: Aspergillosis refers to the disease caused by a species of fungus, Aspergillus. A wide range of manifestations can be observed in the infection by this fungus, including allergic disease, semi-invasive disease and invasive disease. The diagnosis of Aspergillosis is difficult due to the risk of colonization and contamination and the low predictive value of cultures of respiratory samples, mainly sputum. Methodology: The objective of this research project is to determine the clinical correlation between the presence of pulmonary aspergillosis in immunocompromised patients in the Infectology Hospital Dr. Daniel Rodríguez Maridueña, A retrospective, observational and descriptive study was established during the period 2015 to 2017, the chosen universe were patients treated in the area of emergency and hospitalization of the Daniel Rodríguez Maridueña Hospital. The sample consisted of 65 patients who presented several clinical forms of pulmonary aspergillosis. Results: A higher incidence of aspergillosis was observed in patients between 26 and 37 years old, corresponding to 36.9% of the total number of patients in the sample taken. Study found a greater correlation of patients with HIV / AIDS and the presence of Aspergillosis in several of its forms; patients with HIV / AIDS represented 46.2% with a total of 30 patients out of 65 of the sample XIX taken. The forms of clinical presentation of Aspergillosis we found that the form of Invasive Pulmonary Aspergillosis had higher incidence with 25 registered cases. Keywords: HIV, Pulmonary Aspergillosis, Semi Invasive, Invasive, Aspergillone, Nodules, Bronchial asthma, Neutropenia, Tuberculosis
Introduction: Aspergillosis refers to the disease caused by a species of fungus, Aspergillus. A wide range of manifestations can be observed in the infection by this fungus, including allergic disease, semi-invasive disease and invasive disease. The diagnosis of Aspergillosis is difficult due to the risk of colonization and contamination and the low predictive value of cultures of respiratory samples, mainly sputum. Methodology: The objective of this research project is to determine the clinical correlation between the presence of pulmonary aspergillosis in immunocompromised patients in the Infectology Hospital Dr. Daniel Rodríguez Maridueña, A retrospective, observational and descriptive study was established during the period 2015 to 2017, the chosen universe were patients treated in the area of emergency and hospitalization of the Daniel Rodríguez Maridueña Hospital. The sample consisted of 65 patients who presented several clinical forms of pulmonary aspergillosis. Results: A higher incidence of aspergillosis was observed in patients between 26 and 37 years old, corresponding to 36.9% of the total number of patients in the sample taken. Study found a greater correlation of patients with HIV / AIDS and the presence of Aspergillosis in several of its forms; patients with HIV / AIDS represented 46.2% with a total of 30 patients out of 65 of the sample XIX taken. The forms of clinical presentation of Aspergillosis we found that the form of Invasive Pulmonary Aspergillosis had higher incidence with 25 registered cases. Keywords: HIV, Pulmonary Aspergillosis, Semi Invasive, Invasive, Aspergillone, Nodules, Bronchial asthma, Neutropenia, Tuberculosis
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Aspergilosis pulmonar, Inmunosupresión, Asma, Tuberculosis, Virus de inmunodeficiencia humana, Hospital de Infectología Dr. José Daniel Rodríguez Maridueña, Cantón Guayaquil, Ecuador, Epidemiología descriptiva, Estudios retrospectivos