Cambios sistemáticos y orgánicos producidos por el misoprostol en mujeres nulíparas y multíparas con aborto incompleto
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2018
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Universidad de Guayaquil. Facultad de Ciencias Médicas. Carrera de Obstetricia
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El aborto incompleto es la expulsión parcial de tejidos fetales, placentario o líquido amniótico a través de un cérvix uterino con modificaciones y sangrado. Esta morbilidad del embarazo se ha convertido en un problema de salud pública debido a su incidencia cada vez mayor. El Misoprostol es un análogo sintético de prostaglandina usado inicialmente para tratar gatritis por AINES; actualmente se le reconocen efectos multiorgánicos. En ginecología y obstetricia estudios destacan al misoprostol como estimulante miometral con capacidad de aumentar la frecuencia e intensidad de las contracciones del músculo liso uterino, facilitando así la expulsión del contenido uterino. Se trata de un estudio descriptivo observacional, no experimental, y comparativo en mujeres nulípara vs multíparas desarrollado en el Hospital Universitario de Guayaquil, periodo agosto 2017 a enero 2018. El universo fueron todas las pacientes que cumplían criterios de inclusión que fueron 142, la muestra escogida aleatoriamente en base a universo fue de 104 pacientes. Los resultados fueron los siguientes la vía de administración sublingual en dosis de 600 mcg es más usada, dolor pélvico moderado y sangrado transvaginal efectos secundarios más frecuentes, el 12.5% (13 casos) pacientes nulíparas presentaron reblandamiento de cérvix sin dilatación.
Incomplete abortion is the partial expulsion of fetal, placental or amniotic fluid through a uterine cervix with modifications and bleeding. This pregnancy morbidity has become a public health problem due to its increasing incidence. Misoprostol is a synthetic analogue of prostaglandin initially used to treat NSAID gatritis; At present, multi-organ effects are recognized. In gynecology and obstetrics studies highlight misoprostol as a myometrical stimulant with the ability to increase the frequency and intensity of contractions of the uterine smooth muscle, thus facilitating the expulsion of uterine contents. This is an observational descriptive, non-experimental, and comparative study in nulliparous vs multiparous women developed at the University Hospital of Guayaquil, from August 2017 to January 2018. The universe was all the patients that met the inclusion criteria, which were 142, the sample Randomly chosen on a universe basis was 104 patients. The results were the following sublingual administration route in 600 mcg dose is more used, moderate pelvic pain and transvaginal bleeding more frequent side effects, 12.5% (13 cases) nulliparous patients presented cervical softening without dilation.
Incomplete abortion is the partial expulsion of fetal, placental or amniotic fluid through a uterine cervix with modifications and bleeding. This pregnancy morbidity has become a public health problem due to its increasing incidence. Misoprostol is a synthetic analogue of prostaglandin initially used to treat NSAID gatritis; At present, multi-organ effects are recognized. In gynecology and obstetrics studies highlight misoprostol as a myometrical stimulant with the ability to increase the frequency and intensity of contractions of the uterine smooth muscle, thus facilitating the expulsion of uterine contents. This is an observational descriptive, non-experimental, and comparative study in nulliparous vs multiparous women developed at the University Hospital of Guayaquil, from August 2017 to January 2018. The universe was all the patients that met the inclusion criteria, which were 142, the sample Randomly chosen on a universe basis was 104 patients. The results were the following sublingual administration route in 600 mcg dose is more used, moderate pelvic pain and transvaginal bleeding more frequent side effects, 12.5% (13 cases) nulliparous patients presented cervical softening without dilation.
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ABORTO INCOMPLETO, MISOPROSTOL, NULIPARAS, PARIDAD, HOSPITAL UNIVERSITARIO DE GUAYAQUIL, CANTON GUAYAQUIL, ECUADOR