Diabéticos vih positivos en Hospital Dr. José Rodríguez Maridueña entre 2014-2015
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2017
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Universidad de Guayaquil. Facultad de Ciencias Médicas. Escuela de Medicina
Resumen
La terapia antirretroviral de gran amplitud (TARGA) al igual que todo tratamiento farmacológico tiene efectos positivos esperados (aumento de supervivencia) los cuales están siempre condicionados a su uso correcto y adaptado a las circunstancias particulares; teniendo en cuenta que con el uso del tratamiento se manifiestan cambios morfológicos por redistribución grasa (con patrones de lipoatrofia periférica, adiposidad central o lipohipertrofia de diversas distribuciones), dislipemia y alteraciones del metabolismo hidrocarbonado lo que ha dado paso a la aparición de nuevos problemas que significan un cambio en el abordaje clínico de estos pacientes y un nuevo esfuerzo en la comprensión de la fisiopatogenia del propio virus y de las alteraciones que su tratamiento con lleva.
No existe suficiente evidencia de que la terapia antiretroviral en pacientes VIH positivos sea la causante de la aparición de Diabetes Mellitus en los mismos. El sexo que con mayor frecuencia sufre de diabetes y VIH son los hombres. El grupo etario que tiene más predisposición a presentar diabetes mellitus son los mayores de 50 años.
La mayor parte de los pacientes VIH positivos con diabetes provienen de zona urbana. Las principales complicaciones son enfermedades cardiovasculares, enfermedad renal crónica, y neuropatía diabética.
High-amplitude antiretroviral therapy (HAART), like any pharmacological treatment, has expected positive effects (increased survival) which are always conditioned by its correct use and adapted to the particular circumstances; Taking into account that morphological changes due to fat redistribution (with patterns of peripheral lipoatrophy, central adiposity or lipohypertrophy of various distributions), dyslipidemia and alterations of the hydrocarbon metabolism have been manifested, which has given way to the appearance of new problems Mean a change in the clinical approach of these patients and a new effort in the understanding of the pathophysiology of the virus itself and the alterations that its treatment with leads. There is insufficient evidence that antiretroviral therapy in HIV-positive patients is the cause of the occurrence of Diabetes Mellitus in them. The sex that most frequently suffers from diabetes and HIV are men. The age group that is most predisposed to have diabetes mellitus are those older than 50 years. The majority of HIV positive patients with diabetes come from urban areas. The main complications are cardiovascular disease, chronic kidney disease, and diabetic neuropathy.
High-amplitude antiretroviral therapy (HAART), like any pharmacological treatment, has expected positive effects (increased survival) which are always conditioned by its correct use and adapted to the particular circumstances; Taking into account that morphological changes due to fat redistribution (with patterns of peripheral lipoatrophy, central adiposity or lipohypertrophy of various distributions), dyslipidemia and alterations of the hydrocarbon metabolism have been manifested, which has given way to the appearance of new problems Mean a change in the clinical approach of these patients and a new effort in the understanding of the pathophysiology of the virus itself and the alterations that its treatment with leads. There is insufficient evidence that antiretroviral therapy in HIV-positive patients is the cause of the occurrence of Diabetes Mellitus in them. The sex that most frequently suffers from diabetes and HIV are men. The age group that is most predisposed to have diabetes mellitus are those older than 50 years. The majority of HIV positive patients with diabetes come from urban areas. The main complications are cardiovascular disease, chronic kidney disease, and diabetic neuropathy.
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Diabetes mellitus, Virus de inmunodeficiencia humana, Dislipidemia, Hiperglicemia, Hospital de Infectología Dr. José Daniel Rodríguez Maridueña, Cantón Guayaquil, Ecuador