Determinar transaminasa pirúvica como indicador de alteración hepática en mujeres con ingesta de anticonceptivos. Estudio a realizarse en el Laboratorio Clínico de la Maternidad Matilde Hidalgo de Procel, de la ciudad de Guayaquil.
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2014
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Universidad de Guayaquil. Facultad de Ciencias Médicas. Carrera de Tecnología Médica
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El presente estudio se lo realizó en la maternidad “Matilde Hidalgo de Prócel”, conocida como la maternidad del Guasmo en la ciudad de Guayaquil, donde se determinó el alto índice de morbilidad a causa de las alteraciones hepáticas presentadas en un grupo de pacientes que ingieren anticonceptivos orales por tiempos prolongados, por eso el objetivo del presente estudio es la de determinar transaminasa piruvica com indicar de alteración hepática a este grupo de pacientes seleccionadas con las características en mención, en donde se encontró que la consecuencia de la toxicidad a ciertos fármacos como los anticonceptivos y sus componentes químicos, alteran la función normal del hígado como órgano vital, por lo tanto a través de un examen básico y complementario de laboratorio clínico se puede observar la incidencia de la alteración hepática a través del reflejo de elevados niveles de transaminasas. El estudio es de característica analítico, exploratorio y descriptivo, se tomó en consideración para la recolección de la información una muestra de 100 pacientes que asistieron a consulta externa de ginecología, las cuales fueron derivadas a Laboratorio Clínico para determinar transaminasa y cuantificación de los niveles de esta enzima y observar los daños causados por los anticonceptivos a través de los años, se plantean las conclusiones del estudio y las recomendaciones que deberán tener en el control periódico mediante examen de laboratorio para valorar las condiciones de función hepática y tomar medidas de control en implementación de un tratamiento oportuno.
The present study was carried out in the maternity "Matilde Hidalgo de Prócel", known as the maternity of Guasmo in the city of Guayaquil, where the high morbidity index was determined because of the hepatic alterations presented in a group of patients who ingest Oral contraceptives for prolonged periods, for this reason the objective of the present study is to determine pyruvate transaminase and indicate liver alteration in this group of selected patients with the characteristics mentioned, where it was found that the consequence of toxicity to certain drugs such as contraceptives and their chemical components alter the normal function of the liver as a vital organ, therefore, through a basic and complementary clinical laboratory examination, the incidence of hepatic alteration can be observed through the reflection of elevated levels of transaminases. The study is of an analytical, exploratory and descriptive characteristic. A sample of 100 patients who attended the gynecology outpatient clinic was taken into consideration for the collection of the information, which were derived to the Clinical Laboratory to determine transaminase and quantification of the levels of this enzyme and observe the damages caused by contraceptives over the years, the conclusions of the study and the recommendations that should have in the periodic control by means of laboratory examination to assess the liver function conditions and take control measures in implementation of a timely treatment
The present study was carried out in the maternity "Matilde Hidalgo de Prócel", known as the maternity of Guasmo in the city of Guayaquil, where the high morbidity index was determined because of the hepatic alterations presented in a group of patients who ingest Oral contraceptives for prolonged periods, for this reason the objective of the present study is to determine pyruvate transaminase and indicate liver alteration in this group of selected patients with the characteristics mentioned, where it was found that the consequence of toxicity to certain drugs such as contraceptives and their chemical components alter the normal function of the liver as a vital organ, therefore, through a basic and complementary clinical laboratory examination, the incidence of hepatic alteration can be observed through the reflection of elevated levels of transaminases. The study is of an analytical, exploratory and descriptive characteristic. A sample of 100 patients who attended the gynecology outpatient clinic was taken into consideration for the collection of the information, which were derived to the Clinical Laboratory to determine transaminase and quantification of the levels of this enzyme and observe the damages caused by contraceptives over the years, the conclusions of the study and the recommendations that should have in the periodic control by means of laboratory examination to assess the liver function conditions and take control measures in implementation of a timely treatment
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TRANSAMINASA PIRUVICA, ALTERACIONES HEPATICA, ANTCONCEPTIVOS ORALES, HOSPITAL MATERNO INFANTIL DRA. MATILDE HIDALGO DE PROCEL, CANTON GUAYAQUIL, ECUADOR