Resultados de estudio de citomegalovirus mediante utilización de la técnica de ensayo inmunoenzimático (ELISA) estudio a realizarse en el Hospital de Infectología Dr. Daniel Rodríguez Maridueña en pacientes de edad entre 20 a 65 años
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2014
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Universidad de Guayaquil. Facultad de Ciencias Médicas. Carrera de Tecnología Médica
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Citomegalovirus (CMV) pertenece a la familia de los Virus Herpes y se caracteriza por su capacidad para mantenerse en estado latente y asociarse a infecciones recurrentes. El virus se replica in vivo en distintos tipos de células y crece perfectamente sobre fibroblastos. El CMV debe su nombre a que las células infectadas aumentan su tamaño tomando un aspecto redondeado lo que se denomina citomegalia. Por lo que se expuso el objetivo general de desarrollar la técnica de Microelisa en la determinación de citomegalovirus en pacientes de consulta externa del Hospital de Infectología Dr. Daniel Rodríguez. Se realizó la determinación de anticuerpos IgM en 300 pacientes, logrando hacer un diagnóstico acertado en forma oportuna que será la base que permitirá establecer un tratamiento adecuado. El mayor porcentaje de los pacientes Positivos correspondieron a las edades comprendidas entre de 20 - 39 años. En cuanto el nivel de procedencia el mayor porcentaje corresponde a pacientes que pertenecen a la zona marginal con el 61% y los de zona urbana un 39%. El Grupo sanguíneo más representativo dentro de los pacientes de consulta externa con el tipo de sangre O+ con 128 pacientes reflejados en 43%, que donde había el mayor porcentaje de detección positiva del citomegalovirus. Los resultados de este estudio beneficiarán para que en centros asistenciales se observe la importancia de implementar la prueba de CMV en pacientes que presenten síntomas característicos de citomegalovirus.
Cytomegalovirus (CMV) belongs to the Herpes Virus family and is characterized by its ability to stay dormant and be associated with recurrent infections. The virus replicates in vivo in different types of cells and grows perfectly on fibroblasts. CMV owes its name to the fact that infected cells increase in size by taking a rounded appearance called cytomegaly. Therefore, the general objective of developing the Microelisa technique in the determination of cytomegalovirus in outpatients of the Dr. Daniel Rodríguez Infectology Hospital was exposed. The determination of IgM antibodies was carried out in 300 patients, making a successful diagnosis in a timely manner that will be the basis that will allow establishing an appropriate treatment. The highest percentage of Positive patients corresponded to the ages between 20-39 years. As for the level of origin, the highest percentage corresponds to patients belonging to the marginal zone with 61% and those from the urban area 39%. The most representative blood group in the outpatients with the blood type O + with 128 patients reflected in 43%, than where there was the highest percentage of positive cytomegalovirus detection. The results of this study will benefit the importance of implementing the CMV test in patients with symptoms characteristic of cytomegalovirus.
Cytomegalovirus (CMV) belongs to the Herpes Virus family and is characterized by its ability to stay dormant and be associated with recurrent infections. The virus replicates in vivo in different types of cells and grows perfectly on fibroblasts. CMV owes its name to the fact that infected cells increase in size by taking a rounded appearance called cytomegaly. Therefore, the general objective of developing the Microelisa technique in the determination of cytomegalovirus in outpatients of the Dr. Daniel Rodríguez Infectology Hospital was exposed. The determination of IgM antibodies was carried out in 300 patients, making a successful diagnosis in a timely manner that will be the basis that will allow establishing an appropriate treatment. The highest percentage of Positive patients corresponded to the ages between 20-39 years. As for the level of origin, the highest percentage corresponds to patients belonging to the marginal zone with 61% and those from the urban area 39%. The most representative blood group in the outpatients with the blood type O + with 128 patients reflected in 43%, than where there was the highest percentage of positive cytomegalovirus detection. The results of this study will benefit the importance of implementing the CMV test in patients with symptoms characteristic of cytomegalovirus.
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CITOMEGALOVIRUS, INFECCIONES DE HERPESVIRIDAE, ENFERMEDADES INFECCIOSAS, HOSPITAL DE NFECTOLOGIA DR. JOSE DANIEL RODRIGUEZ MARIDUEÑA, CANTON GUAYAQUIL, ECUADOR, METODO DE ELISA, TECNICAS DE LABORATORIO CLINICO, ADULTO, ANCIANO