Eficacia de la nifedipina como agente tocolítico para la amenaza de parto pretérmino
Fecha
2021
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Universidad de Guayaquil. Facultad de Ciencias Médicas. Carrera de Obstetricia
Resumen
El parto pretérmino es un verdadero problema de salud pública, se ha buscado a lo largo de los años buscar un tratamiento efectivo para poder evitarlo; es así que se ha probado con múltiples fármacos tocolíticos, los cuales vayan encaminados a disminuir las contracciones uterinas. Objetivo: Determinar el grado de aplicación y eficacia que tiene el nifedipino como agente tocolitico en las pacientes con amenaza parto pretérmino. Materiales y Métodos: Es un estudio descriptivo, retrospectivo de corte transversal que trabajo con 150 pacientes, en donde los resultados fueron: 30,66% de las pacientes que presentaron amenaza de parto pretérmino tuvieron un rango de edad entre los 18 a 20 años, 40% estuvieron entre las 28 a 32 semanas,46% refirieron hábito tabáquico, las infecciones urinarias se presentaron en un 43,33%, el 80% de las pacientes que recibieron tocolisis no presentaron complicaciones luego de la aplicación respecto al 20% que en cambio si lo presentaron, 65% fue via sublingual, el 40% de las pacientes registraron el efecto entre los 20 a 40 minutos. Conclusiones: El uso de nifedipino como agente tocolitico es seguro en la embarazada porque se asocia a una menor presentación de efectos adversos y favorece una prolongación del embarazo.
Palabras clave: Nifedipino, Eficacia, Complicaciones
Preterm delivery is a true public health problem, it has been sought over the years to find an effective treatment to avoid it; Thus, it has been tried with multiple tocolytic drugs, which are aimed at reducing uterine contractions. Objective: To determine the degree of application and efficacy of nifedipine as a tocolytic agent in patients with threatened preterm delivery. Materials and Methods: It is a descriptive, retrospective, cross-sectional study that worked with 150 patients, where the results were: 30.66% of the patients who presented threatened preterm birth had an age range between 18 to 20 years, 40% were between 28 to 32 weeks, 46% reported smoking, urinary infections occurred in 43.33%, 80% of the patients who received tocolysis did not present complications after application compared to 20% in change if they presented it, 65% was via sublingual, 40% of the patients registered the effect between 20 to 40 minutes. Conclusions: The use of nifedipine as a tocolytic agent is safe in pregnant women because it is associated with a lower presentation of adverse effects and favors a prolongation of pregnancy. Keywords: Nifedipine, Efficacy, Complications
Preterm delivery is a true public health problem, it has been sought over the years to find an effective treatment to avoid it; Thus, it has been tried with multiple tocolytic drugs, which are aimed at reducing uterine contractions. Objective: To determine the degree of application and efficacy of nifedipine as a tocolytic agent in patients with threatened preterm delivery. Materials and Methods: It is a descriptive, retrospective, cross-sectional study that worked with 150 patients, where the results were: 30.66% of the patients who presented threatened preterm birth had an age range between 18 to 20 years, 40% were between 28 to 32 weeks, 46% reported smoking, urinary infections occurred in 43.33%, 80% of the patients who received tocolysis did not present complications after application compared to 20% in change if they presented it, 65% was via sublingual, 40% of the patients registered the effect between 20 to 40 minutes. Conclusions: The use of nifedipine as a tocolytic agent is safe in pregnant women because it is associated with a lower presentation of adverse effects and favors a prolongation of pregnancy. Keywords: Nifedipine, Efficacy, Complications
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Palabras clave
Nifedipino, Amenaza de parto prematuro, Tocolíticos, Epidemiología descriptiva, Estudios retrospectivos, Hospital Materno Infantil Dra. Matide Hidalgo de Procel, Cantón Guayaquil, Ecuador