Utilidad de índice del producto de acumulación lipídica e índice de masa corporal en severidad de psoriasis
Fecha
2021
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Universidad de Guayaquil. Facultad de Ciencias Médicas. Escuela de Graduados
Resumen
La psoriasis es una enfermedad inflamatoria crónica común que afecta a
cualquier edad, clínicamente se caracteriza por pápulas o placas eritematosas bien
delimitadas con escamas micáceas en la superficie, localizadas principalmente en
cuero cabelludo, codos y rodillas, seguidos de las uñas, manos, pies y tronco. El
objetivo principal fue determinar la utilidad del índice del producto de acumulación
lipídica e índice de masa corporal en la severidad de la psoriasis en los pacientes
que acudieron a la consulta externa de Dermatología del hospital Teodoro
Maldonado Carbo. Se realizó un estudio no experimental, observacional de tipo
analítico y correlacional. Se reportó una mediana de 60,5 cm*mmol/l en el índice
del producto de acumulación lipídica y de 30,9 kg/cm2 en el IMC en los pacientes
con psoriasis. El índice LAP fue más alto en la presentación severa, sin embargo,
no se registró una correlación estadísticamente significativa entre la severidad de la
enfermedad y el índice LAP (p=0,4) e IMC (p=0,6). Se registro una correlación
estadísticamente significativa entre el índice LAP y las variables tiempo de
enfermedad, peso, circunferencia de cintura e IMC, reportando valores de p=0,003;
0,003; 0,0001; y 0,002 respectivamente. La medición del índice LAP como
marcador de obesidad visceral permite tamizar a aquellos pacientes con mayor
riesgo cardiovascular en comparación con las mediciones antropométricas
tradicionales de obesidad, con el fin de realizar un diagnóstico precoz y la
implementación de las intervenciones terapéuticas correspondientes.
Palabras claves: Psoriasis, obesidad visceral, índice LAP, índice de masa
corporal, PASI
Psoriasis is a common chronic inflammatory disease that affects any age, clinically characterized by well-defined erythematous papules or plaques with micaceous scales on the surface, located mainly on the scalp, elbows and knees, followed by the nails, hands, feet and trunk. The principal objective was to determine the usefulness of the lipid accumulation product index and body mass index in the severity of psoriasis in patients who attended the Dermatology department from the Teodoro Maldonado Carbo hospital. A non-experimental, observational, analytical and correlational study was carried out. A median of 60.5 cm * mmol / l was reported in the lipid accumulation product index and 30.9 kg / cm2 in the BMI in patients with psoriasis. The LAP index was higher in the severe presentation, however, there was no statistically significant correlation between the severity of the disease and the LAP index (p = 0.4) and BMI (p = 0.6). A statistically significant correlation was recorded between the LAP index and the variables time of illness, weight, waist circumference and BMI, reporting values of p = 0.003; 0.003; 0.0001; and 0.002 respectively. The measurement of the LAP index as a marker of visceral obesity allows screening those patients with higher cardiovascular risk in comparison with traditional anthropometric measurements of obesity, in order to make an early diagnosis and the implementation of the corresponding therapeutic interventions. Keywords: Psoriasis, visceral obesity, LAP index, body mass index, PASI
Psoriasis is a common chronic inflammatory disease that affects any age, clinically characterized by well-defined erythematous papules or plaques with micaceous scales on the surface, located mainly on the scalp, elbows and knees, followed by the nails, hands, feet and trunk. The principal objective was to determine the usefulness of the lipid accumulation product index and body mass index in the severity of psoriasis in patients who attended the Dermatology department from the Teodoro Maldonado Carbo hospital. A non-experimental, observational, analytical and correlational study was carried out. A median of 60.5 cm * mmol / l was reported in the lipid accumulation product index and 30.9 kg / cm2 in the BMI in patients with psoriasis. The LAP index was higher in the severe presentation, however, there was no statistically significant correlation between the severity of the disease and the LAP index (p = 0.4) and BMI (p = 0.6). A statistically significant correlation was recorded between the LAP index and the variables time of illness, weight, waist circumference and BMI, reporting values of p = 0.003; 0.003; 0.0001; and 0.002 respectively. The measurement of the LAP index as a marker of visceral obesity allows screening those patients with higher cardiovascular risk in comparison with traditional anthropometric measurements of obesity, in order to make an early diagnosis and the implementation of the corresponding therapeutic interventions. Keywords: Psoriasis, visceral obesity, LAP index, body mass index, PASI
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Indice de masa corporal, Psoriasis, Obesidad abdominal, Indice del producto de acumulación lipídica, Epidemiología analítica, Hospital de Especialidades Dr. Teodoro Maldonado Carbo, Cantón Guayaquil, Ecuador