Caracterización inmunohistoquimica del cáncer de mama y su correlación con histopatología
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2022
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Universidad de Guayaquil. Facultad de Ciencias Médicas. Escuela de Graduados
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Taxonómicamente la histología del cáncer de mama, no brinda la diferencia biomolecular de los tumores, lo que limita la investigación precisa para brindar la mejor terapéutica y conocer el pronóstico de cada uno de los tumores de mama, por lo que, es menester hacer uso de la inmunohistoquimica. El objetivo de este estudio fue determinar las caracteristicas inmunohistoquimica del cáncer de mama y su correlación histopatológica. Se efectuo un estudio Observacional, retrospectivo y correlacinal que involucra desde el año 2019 al 2021 con información obtenida del Hospital Luis Vernaza. En esta investigación se obtuvo como resultados que tumor de mama mas frecuente según patología fue el carcinoma ductal invasivo 78% todas las pacientes con carcionoma ductal in situ presentaron receptores de estrógeno y progesterona positivos y Ki 67<10% en su gran mayoria ((83%) las pacientes con carcinoma lobulillar invasora presentaron en su gran mayoria (89%) receptores de estrógenos y progesterona positivo.
Taxonomically, the histology of breast cancer does not provide the biomolecular difference of tumors, which limits precise research to provide the best therapy and know the prognosis of each of the breast tumors, so it is necessary to use the immunohistochemistry. The objective of this study was to determine the immunohistochemical characteristics of breast cancer and its histopathological correlation. An observational, retrospective and correlational study was carried out that involves from 2019 to 2021 with information obtained from the Luis Vernaza Hospital. In this investigation it was obtained as results that the most frequent breast tumor according to pathology was invasive ductal carcinoma 78% all patients with ductal carcinoma in situ presented positive estrogen and progesterone receptors and Ki 67 <10% in their great majority ((83 %) patients with invasive lobular carcinoma presented in their great majority (89%) estrogen receptors and positive progesterone.
Taxonomically, the histology of breast cancer does not provide the biomolecular difference of tumors, which limits precise research to provide the best therapy and know the prognosis of each of the breast tumors, so it is necessary to use the immunohistochemistry. The objective of this study was to determine the immunohistochemical characteristics of breast cancer and its histopathological correlation. An observational, retrospective and correlational study was carried out that involves from 2019 to 2021 with information obtained from the Luis Vernaza Hospital. In this investigation it was obtained as results that the most frequent breast tumor according to pathology was invasive ductal carcinoma 78% all patients with ductal carcinoma in situ presented positive estrogen and progesterone receptors and Ki 67 <10% in their great majority ((83 %) patients with invasive lobular carcinoma presented in their great majority (89%) estrogen receptors and positive progesterone.
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Inmunohistoquímica, Neoplasias de la mama, Estudio retrospectivos, Hospital Luis Vernaza, Cantón Guayaquil, Ecuador