Valor diagnostico del aspirado de médula ósea en pacientes con fiebre de origen desconocido vih sida
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2022
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Universidad de Guayaquil. Facultad de Ciencias Médicas. Carrera de Medicina
Resumen
Los pacientes con diagnostico positivo de virus de inmunodeficiencia humana (VIH) suelen presentar fiebre inexplicable. La punción aspirativa de medula ósea (PAMO) es una prueba invasiva útil para guiar el estudio de pacientes que presenten esta dificultad diagnostica. En este estudio, se determinó mediante una toma de muestra al azar de 70 pacientes hospitalizados con diagnóstico de VIH y fiebre de origen desconocido según la base de datos del área de Estadística del Hospital de Infectología Dr. José Rodríguez Maridueña de 2018 a 2020, seleccionando a aquellos que han sido sometidos a Punción aspirativa de medula ósea. Según el estudio realizado, se determinó que de los pacientes sometidos a PAMO el 47,14% obtuvo resultados positivos para enfermedades oportunistas. Se obtuvo como diagnóstico de egreso histoplasmosis, con 37.14%; criptococcosis con 10%; mientras que el 52,86% fueron resultados negativos. En este estudio se propone priorizar el uso de cultivo de la PAMO como prueba diagnóstica de alta sensibilidad y especificidad, a diferencia de otros métodos diagnósticos con menor probabilidad de diagnóstico frente a los diferentes patógenos presentes en pacientes inmunodeprimidos
Patients with a positive diagnosis for Human Immunodeficiency Virus (HIV) usually present unexplained fever. Bone marrow aspiration (BMA) is a useful invasive test to guide the diagnosis of those immunocompromised patients. In this study, it was evaluated random sampling of 70 hospitalized patients with HIV diagnosis and fever of unknown origin, according to the database of the Statistics area of the Hospital of Infectology “Dr. José Rodríguez Maridueña”, from 2018 to 2020; We selected those patients who have undergone BMA puncture. From them, observed that 47.14% were positive for opportunistic diseases, such as histoplasmosis, which was present in 37.14% of patients with hospital discharge; criptococcosis in 10% of patients; while 52.86% were negative for opportunistic infections. In here, we propose to prioritize the use of BMA culture as a diagnostic test with high sensitivity and specificity, in contrast with other diagnostic methods with lower probability of diagnosis different pathogens present in immunocompromised patients
Patients with a positive diagnosis for Human Immunodeficiency Virus (HIV) usually present unexplained fever. Bone marrow aspiration (BMA) is a useful invasive test to guide the diagnosis of those immunocompromised patients. In this study, it was evaluated random sampling of 70 hospitalized patients with HIV diagnosis and fever of unknown origin, according to the database of the Statistics area of the Hospital of Infectology “Dr. José Rodríguez Maridueña”, from 2018 to 2020; We selected those patients who have undergone BMA puncture. From them, observed that 47.14% were positive for opportunistic diseases, such as histoplasmosis, which was present in 37.14% of patients with hospital discharge; criptococcosis in 10% of patients; while 52.86% were negative for opportunistic infections. In here, we propose to prioritize the use of BMA culture as a diagnostic test with high sensitivity and specificity, in contrast with other diagnostic methods with lower probability of diagnosis different pathogens present in immunocompromised patients
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MEDULA OSEA, PUNCION ASPIRACION CON AGUJA FINA, DIAGNOSTICO, FIEBRE, VIRUS DE INMUNODEFICIENCIA HUMANA, SINDROME DE INMUNODEFICIENCIA ADQUIRIDA, REGISTROS MEDICOS, HOSPITAL DE INFECTOLOGIA DR. JOSÉ DANIEL RODRIGUEZ MARIDUEÑA, CANTON GUAYAQUIL, ECUADOR