Perfil microbiológico de candidiasis en hemocultivos de pacientes pediátricos
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2016
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Universidad de Guayaquil. Facultad de Ciencias Médicas. Escuela de Graduados
Resumen
Las infecciones invasivas por hongos incrementa la morbilidad y mortalidad
específicamente en pacientes con sistema inmunológico inmunodeprimidos en un 40 a 60%,
siendo la candidiasis la micosis más frecuente detectada a nivel mundial. La referencia de
candidiasis es de 10 a 20% en infecciones invasoras, Este trabajo se realizó en diferentes
servicios del Hospital Sociedad de lucha contra el Cáncer Solca-Guayaquil, por un período
de 9 meses; comprendido desde 01 Enero al 30 de Septiembre del 2016.Método: de tipo
cuantitativo transversal en el cual se evaluaron pacientes entre edades de 1 a 17 años. Se
utilizó 2 frascos de hemocultivos ,1 aerobio y otro para anaerobios por paciente, en el
monitoreo de los frascos se utilizó sistema automatizado de hemocultivos Bac T Alert/3D
(Biomérieux) y para la identificación el sistema VITEK 2 COMPACT (Biomérieux) muestras
de pacientes pediátricos empleando un volumen mínimo de 3 ml de sangre. Resultados: El
total de muestras de sangre procesadas fueron 449, obteniendo 91 Hemocultivos positivos de
pacientes pediátricos, y de estos 2 fueron positivos para Candida albicans, lo que representa
2,2%. El valor de p 0,989de Cándida con respecto a diagnóstico clínico indica que no hay
relación de los casos positivos con respecto a Leucemia linfocítica aguda, Conclusiones: Se
encontró escasa recuperación de Cándida, inclusive considerando que los pacientes son
leucémicos; por lo que se sugiere implementar un frasco con medio de cultivo para hongos
como mejora a la recuperación.
Palabras clave: candidiasis, hemocultivo, candidemia, levaduras
Invasive fungal infections increase morbidity and mortality specifically in immunocompromised patients by 40 to 60%, with candidiasis being the most frequent mycosis detected worldwide. The reference of candidiasis is from 10 to 20% in invasive infections. This work was carried out in different services of the Hospital Society of Fight against Cancer Solca-Guayaquil, for a period of 9 months; From 01 January to 30 September 2016. Method: a cross-sectional quantitative type in which patients between the ages of 1 and 17 years were evaluated. Two bottles of blood cultures, 1 aerobic and one for anaerobes per patient were used. In the monitoring of the bottles, the automated blood culture system Bac T Alert / 3D (Biomérieux) was used and the VITEK 2 COMPACT (Biomérieux) Pediatric patients using a minimum volume of 3 ml of blood. Results: The total blood samples processed were 449, obtaining 91 Hemocultivos positive of pediatric patients, of which 2 were positive for Candida albicans, representing 2.2%. The value of Candida p 0.989 with respect to clinical diagnosis indicates that there is no relation of the positive cases with respect to Acute lymphocytic leukemia, Conclusions: There was little recovery of Candida, even considering that the patients are leukemic; So it is suggested to implement a flask with half of culture for fungus as an improvement to the recovery.
Invasive fungal infections increase morbidity and mortality specifically in immunocompromised patients by 40 to 60%, with candidiasis being the most frequent mycosis detected worldwide. The reference of candidiasis is from 10 to 20% in invasive infections. This work was carried out in different services of the Hospital Society of Fight against Cancer Solca-Guayaquil, for a period of 9 months; From 01 January to 30 September 2016. Method: a cross-sectional quantitative type in which patients between the ages of 1 and 17 years were evaluated. Two bottles of blood cultures, 1 aerobic and one for anaerobes per patient were used. In the monitoring of the bottles, the automated blood culture system Bac T Alert / 3D (Biomérieux) was used and the VITEK 2 COMPACT (Biomérieux) Pediatric patients using a minimum volume of 3 ml of blood. Results: The total blood samples processed were 449, obtaining 91 Hemocultivos positive of pediatric patients, of which 2 were positive for Candida albicans, representing 2.2%. The value of Candida p 0.989 with respect to clinical diagnosis indicates that there is no relation of the positive cases with respect to Acute lymphocytic leukemia, Conclusions: There was little recovery of Candida, even considering that the patients are leukemic; So it is suggested to implement a flask with half of culture for fungus as an improvement to the recovery.
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CULTIVO DE SANGRE, CANDIDEMIA, CANDIDIASIS, HOSPITAL SOLCA DE GUAYAQUIL, CANTON GUAYAQUIL, ECUADOR, PEDIATRIA, PERFIL MICROBIOLOGICO