Eficacia de la hiperuricemia como predictor de las complicaciones en preeclampsia según factores de riesgo
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2021
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Universidad de Guayaquil. Facultad de Ciencias Médicas. Escuela de Graduados
Resumen
Según varios autores la hiperuricemia tiene un rol patogénico en el desarrollo de la
preeclampsia y sus complicaciones, en el presente trabajo de investigación se
buscó relacionar el impacto que representa en las complicaciones de la
preeclampsia los niveles elevados de ácido úrico en el embarazo según sus
factores de riesgo, en las gestantes entre las 20 – 41 semanas de gestación
atendidas en el Hospital General Guasmo Sur en el periodo enero 2019 – Enero
2020 a través de un estudio: analítico, correlacional, retrospectivo, no experimental
de corte transversal, el análisis se hizo mediante el programa SPSS versión 21.
Las variables del estudio se analizaron con la prueba de Chi cuadrado de
correlación donde se obtuvo un (p valor de ,001) se trabajó además con un índice
de confianza del 95 %, por este motivo se aceptó la hipótesis, en relación a los
valores de ácido úrico para la presencia de complicaciones fue una media de 6.80
mg/dl, las gestantes con hiperuricemia fueron un total de 124 pacientes corresponde
al 53 %, las complicaciones obstétricas se presentaron en el 57 % del total de las
pacientes de ellas el 90 % presentaron hiperuricemia, la vía de terminación del
embarazo fue por cesárea en un 89%, se obtuvo una sensibilidad del 90%,
especificidad del 93 %, valor predictivo positivo del 94 %, valor predictivo negativo
del 88 % lo cual le confiere a la prueba un valor significativo para discriminar
correctamente a los sujetos sanos de los enfermos.
According to several authors, hyperuricemia has a pathogenic role in the development of pre-eclampsia and its complications, in this research work we sought to relate the impact that elevated levels of uric acid in pregnancy represent on complications of pre-eclampsia according to its factors. of risk, in pregnant women between 20 - 41 weeks of gestation attended at the Guasmo Sur General Hospital in the period January 2019 - January 2020 through a study: analytical, correlational, retrospective, non-experimental, cross-sectional, the analysis is made using the SPSS version 21 program. The study variables were analyzed with the Chi-square test of correlation where a (p value of .001) was obtained, and a 95% confidence index was also worked, for this reason the hypothesis was accepted, in relation to the values uric acid for the presence of complications was an average of 7.1 mg / dl, pregnant women with hyperuricemia were a total of 124 patients corresponding to 53%, obstetric complications occurred in 57% of all patients of them 90% had hyperuricemia, the pregnancy termination route was by cesarean section in 89%, a sensitivity of 90%, specificity of 93%, positive predictive value of 94%, negative predictive value of 88% which confers to the test a significant value to correctly discriminate healthy subjects from sick ones.
According to several authors, hyperuricemia has a pathogenic role in the development of pre-eclampsia and its complications, in this research work we sought to relate the impact that elevated levels of uric acid in pregnancy represent on complications of pre-eclampsia according to its factors. of risk, in pregnant women between 20 - 41 weeks of gestation attended at the Guasmo Sur General Hospital in the period January 2019 - January 2020 through a study: analytical, correlational, retrospective, non-experimental, cross-sectional, the analysis is made using the SPSS version 21 program. The study variables were analyzed with the Chi-square test of correlation where a (p value of .001) was obtained, and a 95% confidence index was also worked, for this reason the hypothesis was accepted, in relation to the values uric acid for the presence of complications was an average of 7.1 mg / dl, pregnant women with hyperuricemia were a total of 124 patients corresponding to 53%, obstetric complications occurred in 57% of all patients of them 90% had hyperuricemia, the pregnancy termination route was by cesarean section in 89%, a sensitivity of 90%, specificity of 93%, positive predictive value of 94%, negative predictive value of 88% which confers to the test a significant value to correctly discriminate healthy subjects from sick ones.
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Hiperuricemia, Preeclampsia, Complicaciones del embarazo, Factores de riesgo, Predictor, Estudios retrospectivos, Epidemiología analítica, Hospital General Guasmo Sur, Cantón Guayaquil, Ecuador