Determinación de disfunción pancreática en pacientes con esteatosis pancreática HTMC 2017 - 2018
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2018
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Universidad de Guayaquil. Facultad de Ciencias Médicas. Escuela de Graduados
Resumen
La esteatosis pancreática es una afección muy común, fácilmente diagnosticable, pero a menudo olvidada por médicos e investigadores. Su importancia radica en encontrar una posible correlación entre la enfermedad con la insuficiencia pancreática exocrina, ya que la evidencia actual no es exhaustiva.
Objetivo: Determinar la disfunción pancreática en pacientes con esteatosis pancreática.
Metodología: Estudio observacional, analítico, prospectivo y transversal, que incluyó a 50 pacientes con esteatosis pancreática de la consulta externa de gastroenterología del hospital regional IESS Nº 2 “Teodoro Maldonado Carbo” captados desde el periodo del 1 de agosto del 2017 hasta el 31 de julio del 2018. La gestión de datos se realizó en hojas de cálculo de Microsoft Excel 2010, donde se realizó el procesamiento de datos y para el análisis estadístico se empleó el programa SPSS 21.
Resultados: La prevalencia de esteatosis pancreática en el año 2017-2018 fue del 1% (156) de un total de 13.920 pacientes atendidos durante ese periodo. Se encontró 34% de pacientes con insuficiencia pancreática exocrina demostrada con la prueba de elastasa fecal, siendo el 94% de tipo moderada. De los 17 pacientes con insuficiencia pancreática encontrada en este estudio, el 70,60% (12) presentó infiltración grasa de tipo difusa. Se demostró asociación estadísticamente significativa entre la insuficiencia pancreática con la presencia de factores de riesgo (p = 0,01).
Conclusiones: La esteatosis pancreática se asocia a grados diversos de insuficiencia pancreática exócrina, especialmente cuando hay factores de riesgo asociados, los cuales aumentan 5 veces las probabilidades de desarrollar disfunción de la glándula.
Pancreatic steatosis is a very common condition, easily diagnosed, but often forgotten by doctors and researchers. Its importance lies in finding a possible correlation between the disease and exocrine pancreatic insufficiency, since the current evidence is not exhaustive. Objective: To determine pancreatic dysfunction in patients with pancreatic steatosis. Methodology: An observational, analytical, prospective and cross-sectional study that included 50 patients with pancreatic steatosis from the gastroenterology outpatient clinic of the IESS regional hospital No. 2 "Teodoro Maldonado Carbo", collected from the period of August 1, 2017 to the 31st. July 2018. Data management was done in Microsoft Excel 2010 spreadsheets, where data processing was performed and for the statistical analysis the SPSS 21 program was used. Results: The prevalence of pancreatic steatosis in the year 2017-2018 was 1% (156) out of a total of 13,920 patients treated during that period. We found 34% of patients with exocrine pancreatic insufficiency demonstrated with fecal elastase test, being 94% of moderate type. Of the 17 patients with pancreatic insufficiency found in this study, 70.60% (12) presented diffuse fat infiltration. There was a statistically significant association between pancreatic insufficiency and the presence of risk factors (p = 0.01). Conclusions: Pancreatic steatosis is associated with various degrees of exocrine pancreatic insufficiency, especially when there are associated risk factors, which increase the chances of developing gland dysfunction by 5 times.
Pancreatic steatosis is a very common condition, easily diagnosed, but often forgotten by doctors and researchers. Its importance lies in finding a possible correlation between the disease and exocrine pancreatic insufficiency, since the current evidence is not exhaustive. Objective: To determine pancreatic dysfunction in patients with pancreatic steatosis. Methodology: An observational, analytical, prospective and cross-sectional study that included 50 patients with pancreatic steatosis from the gastroenterology outpatient clinic of the IESS regional hospital No. 2 "Teodoro Maldonado Carbo", collected from the period of August 1, 2017 to the 31st. July 2018. Data management was done in Microsoft Excel 2010 spreadsheets, where data processing was performed and for the statistical analysis the SPSS 21 program was used. Results: The prevalence of pancreatic steatosis in the year 2017-2018 was 1% (156) out of a total of 13,920 patients treated during that period. We found 34% of patients with exocrine pancreatic insufficiency demonstrated with fecal elastase test, being 94% of moderate type. Of the 17 patients with pancreatic insufficiency found in this study, 70.60% (12) presented diffuse fat infiltration. There was a statistically significant association between pancreatic insufficiency and the presence of risk factors (p = 0.01). Conclusions: Pancreatic steatosis is associated with various degrees of exocrine pancreatic insufficiency, especially when there are associated risk factors, which increase the chances of developing gland dysfunction by 5 times.
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ESTEATOSIS PANCREATICA, INSUFICIENCIA PANCREATICA EXOCRINA, FACTORES DE RIESGO, HOSPITAL DE ESPECIALIDADES DR. TEODORO MALDONADO CARBO, CANTON GUAYAQUIL, ECUADOR