Correlación entre Dexmedetomidina y Remifentanilo en anestesia general guiada por Bis en pacientes oncológcos en Hospital Solca Guayaquil, 2013 - 2015
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2016
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Universidad de Guayaquil. Facultad de Ciencias Médicas. Escuela de Graduados
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Desde su llegada al mundo de la anestesiología, el Remifentanilo se ha posicionado de una manera importante como favorito en las anestesias generales por su alta calidad, pero a pesar de sus beneficios no es la droga perfecta ya que si tiene efectos no deseables. La dexmedetomidina, una droga relativamente nueva, que en primeras instancias se las uso en las aéreas de terapia intensiva, estos últimos años entra dentro de las anestesias generales por tener efectos muy atractivos cuando ya se la ha aprendido a usar. Este estudio lleva a una comparación de estas dos drogas, con el objetivo de hallar en la Dexmedetomidina una alternativa al Remifentanilo, encontrarle su verdadera eficacia y conocer los beneficios y desventajas, y de esta proveer al anestesiólogo de hoy una verdadera opción al momento de enfrentarse al reto llamado anestesia general en paciente oncológico. Se realizó un estudio de tipo analítico, correlacional, retrospectivo, con pacientes del hospital Solca Guayaquil en los que se dio anestesia general mediante la revisión de historias clínicas en los años 2013, 2014, 2015, con la hoja de recolección de datos se obtuvoinformación para su respectiva tabulación e interpretación. Se hizo dos grupos de estudios, uno para aquellos en los que se utilizó dexmedetomidina y un segundo grupo para aquellos en los que se empleó remifentanilo, dando un total de 150 pacientes. Como resultado se obtuvo que la Dexmedetomidina da una anestesia general con la misma eficacia de profundidad anestésica comprobada con BIS que el Remifentanilo, con la desventaja de necesidad de más tiempo de inducción y educción pero mejor control de presión arterial y menor incidencia de temblores y escalofríos en el postquirúrgico inmediato
Since its arrival to the world of anesthesiology, remifentanil has positioned itself in a major way as a favorite in the general anesthesia for their high quality, but despite its benefits is not the perfect drug because of the undesirable effects. Dexmedetomidine, a relatively new drug, which is in the first instances use in areas of intensive care, the last few years has begun to be used in general anesthesia for its attractive effects when used adequately.This study leads to a comparison of these two drugs, aiming to find in the dexmedetomidine an alternative to remifentanil, find their true efficacy and know the benefits and disadvantages, and thus provide the anesthetist today a real option when meeting the challenge to call a decision of general anesthesia in oncologic patients.An analytical correlational retrospective study with patients from SOLCA Guayaquil Hospital where has been given general anesthesia by reviewing medical records in 2013, 2014, 2015, for the collection sheet data obtained was performed to obtain information for its respective tabulation and interpretation. Two groups of studies, one for those where dexmedetomidine and a second group for those in which remifentanil was used, obtaining a total of 150 patients.As a result we obtained that dexmedetomidine gives a general anesthesia with the same effectiveness of anesthetic depth expertise with BIS that remifentanil, to the disadvantage of the need for longer induction and eduction but better control of blood pressure and lower incidence of tremors and chills in the immediate postsurgical
Since its arrival to the world of anesthesiology, remifentanil has positioned itself in a major way as a favorite in the general anesthesia for their high quality, but despite its benefits is not the perfect drug because of the undesirable effects. Dexmedetomidine, a relatively new drug, which is in the first instances use in areas of intensive care, the last few years has begun to be used in general anesthesia for its attractive effects when used adequately.This study leads to a comparison of these two drugs, aiming to find in the dexmedetomidine an alternative to remifentanil, find their true efficacy and know the benefits and disadvantages, and thus provide the anesthetist today a real option when meeting the challenge to call a decision of general anesthesia in oncologic patients.An analytical correlational retrospective study with patients from SOLCA Guayaquil Hospital where has been given general anesthesia by reviewing medical records in 2013, 2014, 2015, for the collection sheet data obtained was performed to obtain information for its respective tabulation and interpretation. Two groups of studies, one for those where dexmedetomidine and a second group for those in which remifentanil was used, obtaining a total of 150 patients.As a result we obtained that dexmedetomidine gives a general anesthesia with the same effectiveness of anesthetic depth expertise with BIS that remifentanil, to the disadvantage of the need for longer induction and eduction but better control of blood pressure and lower incidence of tremors and chills in the immediate postsurgical
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ANESTESIA GENERAL, DEXMEDETOMIDINA, REMIFENTANILO, PACIENTES ONCOLOGICOS, EPIDEMIOLOGIA ANALITICA, ESTUDIOS RETROSPECTIVOS, HOSPITAL SOLCA DE GUAYAQUIL, CANTON GUAYAQUIL, ECUADOR