Determinación de hipertriglicerldemia e hiperglicemia como marcadores tempranos de resistencia a la insulina en niños y adolescentes obesos. Hospital del Niño Dr. Francisco de Ycaza Bustamante 2013
No hay miniatura disponible
Fecha
2016
Autores
Título de la revista
ISSN de la revista
Título del volumen
Editor
Universidad de Guayaquil. Facultad de Ciencias Químicas
Resumen
La Obesidad en infantes y adolescentes, constituye un problema de Salud Pública en aumento. La insulinorresistencia es una reducción de respuesta fisiológica de los tejidos diana a la acción de la insulina. La presente investigación tuvo como propósito determinar el valor semiológico de la hipertrigliceridemia e hiperglicemia como marcadores tempranos de resistencia a la insulina en niños y adolescentes obesos, a través del modelo homeostático (HOMA).
El estudio fue de carácter descriptivo y correlacional. La población la constituyeron niños y adolescentes con sobrepeso u obesidad, atendidos en la Consulta Externa del Hospital Dr. Francisco De Ycaza Bustamante. Los resultados en general demostraron la utilidad de parámetros bioquímicos como predictores precoces de insulinorresistencia. Obteniéndose, el 87.9 % de pacientes con obesidad y el 12.09 % con sobrepeso. El promedio más elevado de triglicéridos fue encontrado en el grupo etario de 6 a 10 años y en el sexo masculino, y en cuanto a la glicemia el 18.6 % presentaron valores por encima de los rangos normales. Se puede concluir que de los 47 pacientes con resistencia a la insulina el 85.1 % está clasificado como obeso y que existe asociación entre el IMC, hipertrigliceridemia y la resistencia a la insulina, resultando altamente significativa la asociación entre HOMA-IR y HOMA-p; y HOMA-IR e hipertrigliceridemia (p<0,05)
Obesity in children and adolescents is a public health problem on the rise. Insulin resistance is a reduction target physiological response of the tissue insulin action. With this research it was demonstrated that hypertriglyceridemia and hyperglycemia may be early markers insulin resistance in obese children and adolescents, and homeostatic model assessment (HOMA) is a calculation that helps analyze the insulin resistance. This study was made in a descriptive and correlationaI nature. They constitute the population children and adolescents are overweight or obese treated at the hospital outpatient Dr Francisco De Ycaza Bustamante. The results demonstrated the usefulness of biochemical parameters as early predictors of insulin resistance. They obtained that 87.9% were patients with obesity and overweight were 12.09%. The highest average triglyceride was found in the age group of 6-10 years in males, and in how glucose 18.6% had values aboye the normal range. Tt can be concluded that concluded that of the 47 patients with insulin resistance 85.1% are classified as obese and an association between BM!, hypertriglyceridemia, hyperglycemia and insulin resistance, resulting highly significant association between HOMA-IR and HOMA-p; and HOMA-TR and hypertriglyceridemia. (P « 0.05)
Obesity in children and adolescents is a public health problem on the rise. Insulin resistance is a reduction target physiological response of the tissue insulin action. With this research it was demonstrated that hypertriglyceridemia and hyperglycemia may be early markers insulin resistance in obese children and adolescents, and homeostatic model assessment (HOMA) is a calculation that helps analyze the insulin resistance. This study was made in a descriptive and correlationaI nature. They constitute the population children and adolescents are overweight or obese treated at the hospital outpatient Dr Francisco De Ycaza Bustamante. The results demonstrated the usefulness of biochemical parameters as early predictors of insulin resistance. They obtained that 87.9% were patients with obesity and overweight were 12.09%. The highest average triglyceride was found in the age group of 6-10 years in males, and in how glucose 18.6% had values aboye the normal range. Tt can be concluded that concluded that of the 47 patients with insulin resistance 85.1% are classified as obese and an association between BM!, hypertriglyceridemia, hyperglycemia and insulin resistance, resulting highly significant association between HOMA-IR and HOMA-p; and HOMA-TR and hypertriglyceridemia. (P « 0.05)
Descripción
pdf
Palabras clave
HIPERTRIGLICERIDEMIA, HIPERGLICEMIA, INSULINORRESISTENCIA, OBESIDAD