Factores de riesgo frecuente y comportamiento clínico del cáncer de mama en pacientes de 30 – 70 años atendidos en el Hospital de SOLCA en el período de enero 2013 a 2014
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2015
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Universidad de Guayaquil. Facultad de Ciencias Médicas. Carrera de Medicina
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Antecedentes: el cáncer de mama se ha convertido en un grave problema de salud en el mundo y en Ecuador, este comportamiento epidemiológico no es la excepción. Los factores de riesgo tienen manifestaciones diferentes según diferentes variables y esto justifica la replicación de estudios para estimar la magnitud del riesgo de elementos conocidos. Metodología: Para establecer los factores de riesgo con más impacto en el incremento del riesgo del cáncer de mama y el comportamiento clínico más frecuentes de esta neoplasia en mujeres de 30 a 70 años, Se realizó un estudio transversal y longitudinal en el que se incluyeron 49 mujeres sanas de la ciudad de Guayaquil y 52 con neoplasia de mama comprobado histológicamente atendidas en SOLCA-Guayaquil. Con este propósito se encuestaron mujeres que consintieron su participación, entre las mujeres sin cáncer de mama se excluyeron aquellas que desearon no continuar con la entrevista o en aquellas que se suponían sanas, si existía la sospecha clínica de cáncer de mama o en proceso de estudio por lesión de mama. Resultados: Una edad de 50 años o más (OR 2,769; IC95% 1,201-6,383), el antecedente familiar de cáncer de mama (OR2,373; IC95% 1,063-5,300), y una historia de cáncer de ovario, (OR 14,400; IC95% 1,794-115,581) se asociaron significativamente con el incremento del riesgo de cáncer de mama en mujeres de 30 a 70 años en la ciudad de Guayaquil. Entre las mujeres con cáncer de mama, al momento del diagnostico, la enfermedad se encuentra en estados avanzados Conclusión: No todos los factores tradicionales vinculados al aumento del riesgo de desarrollar cáncer de mama pudieron ser comprobados en el estudio, pero aquellos relacionados con la herencia genética y la edad determinan el riesgo más alto en nuestro medio. Palabras Clave: cáncer de mama. Manifestacionesclínicas. Riesgo. Pronóstico
Background: Breast cancer has become a serious health problem in the world and in Ecuador, the epidemiological behavior is no exception. Risk factors take different forms according to different variables and this justifies replication studies to estimate the magnitude of the risk of known elements. Methodology: To establish risk factors with the greatest impact on the increased risk of breast cancer and the clinical behavior of these tumors in women aged 3070 years is frequently a cross-sectional study that included 49 healthy women was conducted city of Guayaquil and 52 with breast neoplasm histologically proven SOLCA served in Guayaquil. For this purpose consenting women participation among women without breast cancer those who wished not to continue with the interview or those that were supposed healthy, if there was a clinical suspicion of breast cancer or being excluded study surveyed breast injury. Results: An age of 50 or older (OR 2.769, 95% CI 1.201 to 6.383), family history of breast cancer (OR2,373, 95% CI 1.063 to 5.300), and a history of ovarian cancer (OR 14,400 ; 95% CI 1.794 to 115.581) were significantly associated with increased risk of breast cancer in women aged 30-70 years in the city of Guayaquil. Among women with breast cancer at diagnosis, the disease is in advanced stages Conclusion: Not all traditional factors linked to increased risk of developing breast cancer could be tested in the study, but those related to genetics and age determine the highest risk in our midst. Keywords: breast cancer. Clinical manifestations. Risk. Outcome.
Background: Breast cancer has become a serious health problem in the world and in Ecuador, the epidemiological behavior is no exception. Risk factors take different forms according to different variables and this justifies replication studies to estimate the magnitude of the risk of known elements. Methodology: To establish risk factors with the greatest impact on the increased risk of breast cancer and the clinical behavior of these tumors in women aged 3070 years is frequently a cross-sectional study that included 49 healthy women was conducted city of Guayaquil and 52 with breast neoplasm histologically proven SOLCA served in Guayaquil. For this purpose consenting women participation among women without breast cancer those who wished not to continue with the interview or those that were supposed healthy, if there was a clinical suspicion of breast cancer or being excluded study surveyed breast injury. Results: An age of 50 or older (OR 2.769, 95% CI 1.201 to 6.383), family history of breast cancer (OR2,373, 95% CI 1.063 to 5.300), and a history of ovarian cancer (OR 14,400 ; 95% CI 1.794 to 115.581) were significantly associated with increased risk of breast cancer in women aged 30-70 years in the city of Guayaquil. Among women with breast cancer at diagnosis, the disease is in advanced stages Conclusion: Not all traditional factors linked to increased risk of developing breast cancer could be tested in the study, but those related to genetics and age determine the highest risk in our midst. Keywords: breast cancer. Clinical manifestations. Risk. Outcome.
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Neoplasias de la mama, Signos y síntomas, Hospital SOLCA de Guayaquil, Cantón Guayaquil, Ecuador, Factores de riesgo