Factores asociados a fracaso terapeútico en pacientes con tuberculosis multidrogorresistente en el Hospital General Guasmo Sur Guayaquil
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2019
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Universidad de Guayaquil. Facultad de Ciencias Médicas. Carrera de Medicina
Resumen
Introducción: La OMS en el 2015, calculo que aproximadamente se habían manifestado cerca
de 10 millones de casos de TB en el 2014, de estos pacientes el 5% presentaron cepas
multirresistentes (MDR). Una de las causas principales es que a menudo los pacientes que
presentan TB no toman su medicación como es debido
Objetivo: Determinar los factores asociados a fracaso terapéutico en pacientes con
Tuberculosis Multidrogorresistente en el Hospital General Guasmo Sur en el año 2018.
Metodología: Estudio presenta con enfoque retrospectivo, descriptivo, analítico de corte
transversal en el cual se utilizó como fuente de información historias clínicas de pacientes que
presentaron TB-MDR, del Hospital General Guasmo Sur,
Resultados: El contacto con pacientes con TB-MDR encabeza este grupo de factores ya que se
presentó en el 82,1% de los casos de estudio, El abandono de tratamiento antifímico se presenta
en el 68,7% de los casos, y el VIH como comorbilidad se reportó en más del 80% del grupo de
estudio.
Recomendaciones: Cumplir la recomendación de la OMS con respecto al Sistema de
Tratamiento por Observación Directa en cada uno de los Centros de Salud del país
Introduction: In 2015, WHO estimated that approximately 10 million cases of TB had manifested in 2014; of these patients, 5% had multiresistant strains (MDR). One of the main causes is that often patients who have TB do not take their medication properly. Objective: To determine the factors associated with therapeutic failure in patients with Mulltidrogorresostent Tubercles in the Guasmo Sur General Hospital in 2018. Methodology: This study presents a retrospective, descriptive and analytical cross-sectional approach in which clinical records of patients presenting with MDR-TB from the Guasmo Sur General Hospital were used as a source of information. Results: The contact with patients with MDR-TB leads this group of factors since it occurred in 82.1% of the case studies. The abandonment of antifungal treatment occurs in 68.7% of the cases, and the HIV as comorbidity was reported in more than 80% of the study group. Recommendations: Comply with the recommendation of the WHO regarding the Treatment System by Direct Observation in each of the Health Centers of the country
Introduction: In 2015, WHO estimated that approximately 10 million cases of TB had manifested in 2014; of these patients, 5% had multiresistant strains (MDR). One of the main causes is that often patients who have TB do not take their medication properly. Objective: To determine the factors associated with therapeutic failure in patients with Mulltidrogorresostent Tubercles in the Guasmo Sur General Hospital in 2018. Methodology: This study presents a retrospective, descriptive and analytical cross-sectional approach in which clinical records of patients presenting with MDR-TB from the Guasmo Sur General Hospital were used as a source of information. Results: The contact with patients with MDR-TB leads this group of factors since it occurred in 82.1% of the case studies. The abandonment of antifungal treatment occurs in 68.7% of the cases, and the HIV as comorbidity was reported in more than 80% of the study group. Recommendations: Comply with the recommendation of the WHO regarding the Treatment System by Direct Observation in each of the Health Centers of the country
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Resistencia a medicamentos, Tuberculosis, Factores de riesgo, Epidemiología descriptiva, Epidemiología analítica, Estudios retrospectivos, Hospital General Guasmo Sur, Cantón Guayaquil, Ecuador, Fracaso terapeútico