Rinitis alérgica correlación de inmunoglobulina E por quimioluminiscencia y citologia nasal por tinción de wright.
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2013
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Universidad de Guayaquil. Facultad de Ciencias Médicas. Carrera de Tecnología Médica
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La rinitis alérgica se caracteriza por síntomas de picor nasal, estornudos, rinorrea, taponamiento y, en ocasiones, disminución del sentido del olfato. No es ninguna enfermedad fatal e incluso, a menudo, es trivializada, pero comporta una considerable morbilidad y los que la han experimentado saben los padecimientos que se sufren por la misma. Además, es muy frecuente que, junto con las desagradables molestias nasales, el enfermo presente malestar general, cefalea, sinusitis por deterioro del drenaje de los senos, alteraciones del sueño con problemas de concentración al día siguiente, junto con dificultades en el diario vivir, la rinitis alérgica es un problema global de salud pública. Su elevada prevalencia, la existencia de enfermedades comórbidas, la afectación de la calidad de vida del paciente y los elevados gastos que ocasiona son razones suficientes para considerarla como una de las enfermedades de mayor impacto sanitario. No obstante, y a menudo es una enfermedad soslayada y, por consiguiente, subdiagnosticada y subtratada, por este motivo esta tesis presenta como objetivo principal el estudio de las alteraciones que presentan los pacientes con Rinitis alérgica con correlación con IgE por quimioluminiscencia y citología del moco nasal por tinción de Wright, con la caracterización de las técnicas que se emplean en la determinación de la IgE y determinación de mastocitos por tinción de Wright, la rinitis alérgica es una entidad frecuente en todas las edades se asocia con otros síndromes alérgicos como asma, dermatitis atópica, sinusitis, conjuntivitis. Se caracteriza por inflamación crónica de la mucosa nasal debida a la liberación de enzimas producidas por la interacción de anticuerpos IgE que sensibilizan mastocitos y células inflamatorias , además de la liberación de sustancias inflamatorias como histamina ,y alérgenos, enzimas que actúan sobre vasos, glándulas y receptores neurogénicos. Los aereoalérgenos en ocasiones pueden ser diferentes en cuanto al lugar de localización.
Allergic rhinitis is characterized by symptoms of nasal itching, sneezing, runny nose, tamponade and, occasionally, decreased sense of smell. It is not a fatal disease and it is often trivialized, but it entails considerable morbidity and those who have experienced it know the sufferings suffered by it. In addition, it is very common that, along with unpleasant nasal discomfort, the patient has general malaise, headache, sinusitis due to deterioration of the sinus drainage, sleep disturbances with problems of concentration the next day, along with difficulties in daily life, Allergic rhinitis is a global public health problem. Its high prevalence, the existence of comorbid diseases, the affectation of the quality of life of the patient and the high expenses that it causes are sufficient reasons to consider it as one of the diseases with the greatest sanitary impact. However, and often it is a neglected disease and, therefore, underdiagnosed and subtracted, for this reason this thesis has as main objective the study of the alterations presented by patients with allergic rhinitis correlated with IgE by chemiluminescence and cytology of nasal mucus. by Wright's stain, with the characterization of the techniques used in the determination of IgE and determination of mast cells by Wright stain, allergic rhinitis is a frequent entity at all ages is associated with other allergic syndromes such as asthma, dermatitis atopic, sinusitis, conjunctivitis. It is characterized by chronic inflammation of the nasal mucosa due to the release of enzymes produced by the interaction of IgE antibodies that sensitize mast cells and inflammatory cells, in addition to the release of inflammatory substances such as histamine, and allergens, enzymes that act on vessels, glands and Neurogenic receptors. Aereoallergens may sometimes be different in location.
Allergic rhinitis is characterized by symptoms of nasal itching, sneezing, runny nose, tamponade and, occasionally, decreased sense of smell. It is not a fatal disease and it is often trivialized, but it entails considerable morbidity and those who have experienced it know the sufferings suffered by it. In addition, it is very common that, along with unpleasant nasal discomfort, the patient has general malaise, headache, sinusitis due to deterioration of the sinus drainage, sleep disturbances with problems of concentration the next day, along with difficulties in daily life, Allergic rhinitis is a global public health problem. Its high prevalence, the existence of comorbid diseases, the affectation of the quality of life of the patient and the high expenses that it causes are sufficient reasons to consider it as one of the diseases with the greatest sanitary impact. However, and often it is a neglected disease and, therefore, underdiagnosed and subtracted, for this reason this thesis has as main objective the study of the alterations presented by patients with allergic rhinitis correlated with IgE by chemiluminescence and cytology of nasal mucus. by Wright's stain, with the characterization of the techniques used in the determination of IgE and determination of mast cells by Wright stain, allergic rhinitis is a frequent entity at all ages is associated with other allergic syndromes such as asthma, dermatitis atopic, sinusitis, conjunctivitis. It is characterized by chronic inflammation of the nasal mucosa due to the release of enzymes produced by the interaction of IgE antibodies that sensitize mast cells and inflammatory cells, in addition to the release of inflammatory substances such as histamine, and allergens, enzymes that act on vessels, glands and Neurogenic receptors. Aereoallergens may sometimes be different in location.
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DERMATITIS ATOPICA, ASMA, CEFALEA, RINITIS ALERGICA, HOSPITAL DE ESPECIALIDADES DR. TEODORO MALDONADO CARBO, CANTON GUAYAQUlL, ECUADOR, INMUNOGLOBULINA E, QUIMIOLUMINISCENCIA, TINCION DE WRIGHT